Abstract：Objective To ana1yze the c1inica1 patho1ogica1 characteristics and prognosis of uterine carcinosarcoma，and to provide re1iab1e reference basis for the c1inica1 diagnosis and treatment for uterine carcinosarcoma.Methods From January 2007 to March 2016，60 uterine carcinosarcoma patients with successfu1 fo11ow-up for 5 years were se1ected as the research objects.The c1inica1 data of patients were retrospective ana1yzed.The c1inica1 patho1ogica1 characteristics of uterine sarcoma patients were ana1yzed，and the surgica1 treatment and prognosis were observed.Patients were divided into surviva1 group and death group according to death situation of uterine carcinosarcoma patients.Sing1e factor ana1ysis and mu1tip1e factors Logistic regression ana1ysis were used to ana1yze the re1ated factors that impacted the prognosis of uterine carcinosarcoma.Results The uterine vo1ume of 60 uterine sarcoma patients were abnorma1，tumors in uterine cavity showed cau1if1ower or po1ypoid，different degrees of hemorrhage and necrosis were present on the surface of the tumors，the epithe1ia1 ce11s of the uterus sarcoma showed differentiation under the microscope and a11 invaded the uterine muscu1ar 1ayer.5 years fo11ow-up found 42 of the 60 patients died，18 patients survived successfu11y and the 5 years surviva1 rate was 30%.Sing1e factor ana1ysis showed that the tumor size，depth of muscu1ar invasion，1ymph node metastasis，TNM staging of tumor and postoperative residua1 disease between surviva1 group and death group had obvious difference（P＜0.05）；Mu1tip1e factors Logistic regression ana1ysis affirmed that depth of muscu1ar invasion，1ymph node metastasis，TNM staging of tumor and postoperative residua1 disease were main1y risk factors that impacted uterine carcinosarcoma.Conclusion The morta1ity rate of uterine sarcoma is high and the prognosis is affected by depth of muscu-1ar invasion，1ymph node metastasis，TNM staging of tumor and postoperative residua1 disease.More targeted treatment for the above inf1uencing factors shou1d be made in c1inica1 to improve the prognosis.
AghajanianC，Si11MW，SecordAA，etal.Iniparibp1us pac1itaxe1 and carbop1atin as initia1 treatment of advanced or recurrent uterine carcinosarcoma：a gyneco1ogic onco1ogy group study［J］.Gyneco1 Onco1，2012，126（3）：424-427.
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Kowa1ewska M，Danska-Bidzinska A，Baku1a-Za1ewska E，et al.Identification of suitab1e reference genes for gene expressionmeasurementinuterinesarcomaand carcinosarcoma tumors［J］.C1in Biochem，2012，45（4-5）：368-371.
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