Abstract:Objective To explore the clinical effect of Cefoperazone sodium/Sulbactam sodium(Shupushen)in the treatment of pulmonary infection in the elderly patients.Methods Clinical data of 200 cases of elderly patients with pulmonary infection in our hospital from March 2012 to January 2015 were retrospective analyzed.According to the different treatment methods,all patients were divided into the Zuoke group and the Shupushen group,100 cases in each group.The Zuoke group was given Levofloxacine hydrochloride injection (Zuoke),the Shupushen group was given Shupushen.The total effective rate,the incidence rate of side effects of drugs and the level of IL-6,CRP,WBC and TNF-α before and after the intervention was compared between the two groups respectively.Results There was no significant difference in the total effective rate between the two groups in the treatment of pulmonary infection (P>0.05).The level of IL-6,CRP,WBC and TNF-αafter the intervention in the Shupushen group was better than that in the Zuoke group,with significant difference (P<0.05).The incidence rate of side effects of drugs in the Shupushen group was lower than that in the Zuoke group,with significant difference(P<0.01).Conclusion Clinical effect of Shupushen in the treatment of pulmonary infection in the elderly patients is exact,which can effectively improve clinical symptoms,reduce the level of inflammation of the body,and less side effects,higher safety,it isworthy of clinical promotion and application.
马花平. 头孢哌酮钠/舒巴坦钠(舒普深)治疗老年人肺部感染的临床分析[J]. 中国当代医药, 2016, 23(24): 115-117.
MA Hua-ping. Clinical analysis of Cefoperazone sodium/Sulbactam sodium(Shupushen)in the treatment of pulmonary infection in the elderly patients. 中国当代医药, 2016, 23(24): 115-117.
Su YC,Townsend D,Herrero LJ,et al.Dual proinflammatory and antiviral properties of pulmonary eosinophils in respiratory syncytial virus vaccine-enhanced disease[J].J Virol,2015,89(3):1564-1578.