Abstract：Objective To explore the application value of Levofloxacin in the patients with initial treatment of pulmonary tuberculosis.Methods 58 patients with initial treatment of pulmonary tuberculosis in our hospital from October 2012 to March 2014 were selected and divided into the control group （conventional anti-tuberculosis treatment group）and the observation group （conventional treatment and Levofloxacin group）according to themethod of random number table，29 cases in each group.The sputum negative conversion rates and lesion absorption rates at the second，fourth and sixth month after the treatment，pulmonary function indexes before the treatment and at the second，fourth and sixth month after the treatmentwas compared between the two groups.Results The sputum negative conversion rates and and lesion absorption rates in the observation group at the second，fourth and sixthmonth after the treatmentwas higher than that in the control group，with significant difference （P＜0.05）.The level of VC，MMF，MVV，FEV1.0 in the observation group at the second，fourth and sixth month after the treatmentwas better than that in the control group，with significant difference （P＜0.05）.Conclusion The application value of Levofloxacin in the patients with initial treatment of pulmonary tuberculosis is higher，and its role for the improvement of respiratory function state is obvious.
龚诗. 左氧氟沙星在初治肺结核患者中的应用价值[J]. 中国当代医药, 2016, 23(24): 113-114转120.
GONG Shi. App lication value of Levofloxacin in the patients with initial treatment of pulmonary tuberculosis. 中国当代医药, 2016, 23(24): 113-114转120.
Dames Silva KK，Lopes AJ，Jansen JM，etal.Total inspiratory and expiratory impedance in patients with severe chronic obstructive pulmonary disease［J］.Clinics（Sao Paulo），2011，66（12）：2085-2091.
Marinho LS，Sousa NP，Barbosa CA，et al.Assessment of regional lung ventilation by electrical impedance tomography in a patient with unilateral bronchial stenosis and a history of tuberculosis［J］.JBras Pneumol，2013，39（6）：742-746.
Bedini A，Garlassi E，Stentarelli C，et al.Multidrugresistant tuberculosis outbreak in an Italian prison：tolerance of pyrazinamide plus levofloxacin prophylaxis and serial interferon gamma release assays［J］.New Microbes New Infect，2016，7（12）：45-51.
京公网安备 11010502046607号