1.Department of Anesthesia，People′s Hospital of Ganzhou City in Jiangxi Province，Ganzhou 341000，China；
2.Department of Liver Disease，the Fifth People′s Hospital of Ganzhou City in Jiangxi Province，Ganzhou 341000，China
Objective To evaluate the effect of Dexmedetomidine combined with topical anesthesia used for airway foreign body removal in children. Methods Ninety pediatric patients undergoing rigid bronchoscopy examination2，MAP were recorded at four time point：before inhalation anesthesia （T0），at 15min after topical anesthesia （T1），at 1 and 5min after inserting bronchoscope （T2，T3）.Adverse reaction after anesthesia，in the process of bronchoscopy and after operation，and anesthesia handle and so on.Results Compared with group R and T，HR，RR and MAP wasmore stable in group D，SpO2is not as stable as group T，but it could be acceptable level after inhaling of oxygen.Compared with group R and T，the complications such as nausea，cough，holding breath，respiratory depression，laryngospasm，bronchospasm and restlessness throughout the procedure was less in group D.The occurrence rate of bradycardia is higher in group D，but it can be prevention and treatment by Atropine injection.Conclusion Dexmedetomidine combined with topical anesthesia used for airway foreign body removal in children is a safe and feasiblemethod receivedby our hospital from January 2015 to August 2016 were selected and randomly divided into three groups：Dexmedetomidine+Propofol+topical anesthesia group（group D），simple topical anesthesia group（group T）and Remifentanil+Propofol+ topical anesthesia group （group R），and there were 30 cases in each group.All patients inhaled Sevoflurane for anesthesia induction and then given topical anesthesia （Lidocaine of 2mg/kg）.In group D，Propofol of 0.15mg/（kg·min）for continuous intravenous infusion and Dexmedetomidine of 4μg/（kg·h）for intravenous infusion for loading dose，and then 4μg （kg·min）were continuously infusion until the end of surgery，the patients inhaled Sevoflurane until before surgery.In group R，Propofol of 0.10mg/（kg·min）for intravenous infusion and Remifentanil of 0.1μg/（kg·min）were administered until the end of surgery.In group T，the patients given Sevoflurane for continuousmask inhalation for 15minutes.In the whole process of anesthesia，all patients kept their own breathin.HR，RR，SpO
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