Abstract:Objective To investigate the clinical efficacy of Mesalazine combined with probiotics in the treatment of ulcerative colitis.Methods A total of 80 patients with ulcerative colitis diagnosed and treated in the Fifth Affiliated(Zhuhai) Hospital of Zunyi Medical University from January 2019 to January 2021 were selected as the research objects and divided into the control group and the observation group by random number table method, with 40 cases in each group.Mesalazine was treated in the control group and Mesalazine combined with probiotics was treated in the observation group.The treatment effect and serum C-reactive protein level before and after treatment were compared between the two groups.Results The total effective rate of observation group was 97.50%, higher than 85.00% of control group,and the difference was statistically significant (P<0.05).After treatment, the levels of serum C-reactive protein in the two groups were lower than those before treatment, and the level of serum C-reactive protein in observation group was lower than that in control group, the differences were statistically significant (P<0.05).Conclusion In the treatment of ulcerative colitis, the combination of Mesalazine and probiotics is better, can improve patients′ clinical symptoms, and the effect is better.It is worthy of clinical promotion and treatment.
刘畅; 李国帆. 美沙拉嗪联合益生菌治疗溃疡性结肠炎的临床效果[J]. 中国当代医药, 2021, 28(36): 41-43.
LIU Chang; LI Guofan. Clinical effect of Mesalazine combined with probiotics in the treatment of ulcerative colitis. 中国当代医药, 2021, 28(36): 41-43.
Zhong C,Cheng X,Jia B,et al.Gancao Xiexin decoction combined with mesalazine in the treatment of ulcerative colitis:A protocol for a systematic review and meta -analysis [J].Medicine,2020,99(47):e23038.