Abstract：Objective To explore the effect of laparoscopic cholecystectomy (LC) on gastrointestinal function and levels of inflammatory factors in patients with acute cholecystitis.Methods A total of 300 patients with acute cholecystitis admitted to Jinzhou Central Hospital from November 2017 to November 2019 were retrospectively analyzed.According to different surgical methods,they were divided into the control group (145 cases) and the observation group (155 cases).Three-hole LC was used in the control group,and in the observation group,single-hole LC was adopted.The perioperative indicators,gastrointestinal function and changes of inflammatory factors mainly including C-reactive protein(CRP),tumor necrosis factor-α (TNF-α) and interleukin-6 (IL-6) before surgery and 3 days after surgery,and complications of the two groups were compared.Results The operation time,exhaust time and hospital stay of the observation group were shorter than those of the control group,and the bleeding volume during operation was less than that of the control group,the differences were statistically significant (P＜0.05).The recovery time of bowel sounds,food ingestion time and defecation time in the observation group were shorter than those in the control group,and the differences were statistically significant (P＜0.05).The levels of CRP,TNF-α and IL-6 3 days after surgery were lower than those before operation,and the levels of CRP,TNF-α and IL-6 in the observation group were lower than the control group at 3 days after surgery,and the differences were statistically significant (P＜0.05).The total incidence of complications in the observation group was lower than the control group,and the difference was statistically significant (P＜0.05).Conclusion The effect of single-hole LC in patients with acute cholecystitis is favorable,which can significantly reduce the operation time and hospital stay,improve gastrointestinal function and the levels of inflammatory factors,decrease postoperative complications,and faciliate the prognosis of patients.It is worthy of clinical promotion.
李帅. 腹腔镜胆囊切除术对急性胆囊炎患者胃肠功能及炎症因子水平的影响[J]. 中国当代医药, 2021, 28(9): 93-95转99.
LI Shuai. Effect of laparoscopic cholecystectomy on gastrointestinal function and inflammatory factor levels in patients with acute cholecystitis. 中国当代医药, 2021, 28(9): 93-95转99.
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