Abstract:]Objective To investigate the clinical effect of laparoscopic splenectomy combined with pericardial vascular dissection in the treatment of portal hypertension of liver cirrhosis.Methods From January 2018 to January 2019,54 patients with portal hypertension of liver cirrhosis were selected as the research objects,and they were divided into the experimental group (27 cases,laparoscopic splenectomy+pericardial vascular dissection) and the control group (27 cases,open splenectomy+pericardial vascular dissection) according to the random number table method.The surgical success rate and incidence of complications of the two groups were statistically analyzed,and the basic operation indexes and improvement of esophageal and gastric varices of the two groups were observed to evaluate the efficacy and safety.Results Both groups successfully completed the operation,with a success rate of 100%.The total incidence of complications in the experimental group (7.41%) was lower than that in the control group (25.93%),the intraoperative blood loss ([325.8±74.2]mL) was less than that of the control group ([453.0±91.6]mL),the first exhaust time ([1.4±0.3]d)was shorter than that of the control group ([2.7±0.5]d),and the differences were statistically significant (χ2=6.814,t=7.614,3.196,P<0.05).After electronic gastroscopy,esophageal and gastric varices improved or disappeared in different degrees in the two groups.No upper gastrointestinal bleeding occurred during the follow-up of 1 year.The effective rate of treatment was 100%.Conclusion Laparoscopic splenectomy combined with pericardial vascular dissection can effectively improve the symptoms of esophagogastric varices and prevent upper gastrointestinal bleeding,which can achieve the same effect as open surgery in the treatment of cirrhotic portal hypertension,with fewer complications,faster postoperative recovery and higher clinical promotion value.