Analysis of correlative influencing factors of CAD
WANG Hui1 ZHANG Kui2 WANG Yang3▲
1.Department of Cadre Health Care and Geratology,Shihezi Municipal People′s Hospital,Xinjiang Uygur Autonomous Region,Shihezi 832000,China;
2.Department of Intensive Care Unit,Shihezi Municipal People′s Hospital,Xinjiang Uygur Autonomous Region,Shihezi 832000,China;
3.Department of Basic Medicine,Shihezi University School of Medicine,Xinjiang Uygur Autonomous Region,Shihezi 832000,China
Abstract：Objective To investigate the factors influencing of coronary artery disease (CAD).Methods A total of 1086 consecutive patients who were enrolled in the Shihezi Municipal People′s Hospital from January 2018 to December 2019 were selected as subjects.In accordance with the World Health Organization (WHO) diagnosis standard of CAD,they were divided into CAD group (666 cases) and non-CAD group (420 cases).General information on all patients was collected.The biochemical characteristics were examined,and multiple factors were analyzed by Logistic regression analysis.Results Unifactor analysis showed that the proportion of male,age,the proportion of smoking,the proportion of hypertension,the proportion of diabetes and uric acid level in the CAD group were higher than those in the non-CAD group,and the high-density lipoprotein cholesterol level was lower than that in the non-CAD group,with statistically significant differences (P＜0.05).The results of multivariate Logistic regression analysis showed that male (β=0.452,OR=1.571,95%CI=1.048-2.356),advanced age (β=0.053,OR=1.055,95%CI=1.041-1.068),smoking (β=0.697,OR=2.007,95%CI=1.359-2.963),diabetes (β=0.618,OR=1.856,95%CI=1.352-2.548),high uric acid (β=0.002,OR=1.002,95%CI=1.000-1.003) were the risk factors for CAD (P＜0.05),high density lipoprotein cholesterol (β=-0.708,OR=0.493,95%CI=0.333-0.730) was the protection factor for CAD (P＜0.05).Conclusion The present study indicates that high uric acid,being male,advanced age,smoking,and diabetes may be risk factors for CAD,while high density lipoprotein cholesterol may be a protective factor for CAD.
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