Abstract：Objective To investigate the clinical effect of Atorvastatin combined with Trimetazidine in the treatment of angina pectoris patients with coronary heart disease. Methods A total of 100 patients with coronary heart disease and angina pectoris admitted to our hospital from January 2018 to March 2019 were selected as the research objects.According to different treatment schemes, they were divided into the experimental group (50 cases) and the control group(50 cases).The experimental group was treated with Atorvastatin combined with Trimetazidine, while the control group was treated with Trimetazidine.The treatment effect, blood lipid levels before and after treatment, angina pectoris frequency and duration were compared between the two groups. Results The total effective rate of the experimental group was higher than that of the control group, and the difference was statistically significant (P＜0.05).The levels of lowdensity lipoprotein cholesterol (LDL-C), triglyceride (TG) and total cholesterol (TC) in the two groups after treatment were lower than those before treatment, and the levels of high-density lipoprotein cholesterol (HDL-C) in the two groups were higher than those before treatment, with statistically significant differences (P＜0.05).After treatment, the levels of LDL-C, TG and TC in the experimental group were lower than those in the control group, and the level of HDL-C was higher than that in the control group, with statistically significant differences (P＜0.05).After treatment, the number of angina attacks in the two groups was fewer than that before treatment, and the attack time was shorter than that before treatment, with statistically significant differences (P＜0.05).After treatment, the number of angina attacks in the experimental group was fewer than that in the control group, and the duration of the attacks was shorter than that in the control group, with statistically significant differences (P＜0.05). Conclusion Patients with coronary heart disease and angina pectoris receive Atorvastatin and Trimetazidine in combination, the effect is good, and it can improve the blood lipid treated with of patients.
郑熙. 阿托伐他汀联合曲美他嗪治疗冠心病心绞痛患者的临床效果[J]. 中国当代医药, 2020, 27(15): 56-58转62.
ZHENG Xi. Clinical effect of Atorvastatin combined with Trimetazidine in the treatment of angina pectoris of coronary heart disease. 中国当代医药, 2020, 27(15): 56-58转62.
Athyros VG，Papageorgiou AA，Mercouris BR，et al.Treatment with atorvastatin to the National Cholesterol Educational Program goal versus "usual" care in secondary coronary heart disease prevention.The GREek Atorvastatin and Coronary-heart-disease evaluation (GREACE) study[J].Curr Med Res Opin，2002，18（4）：220-228.
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