Abstract:Objective To investigate the application of trans-cervical resection of polyps (TCRP) regimen combined with estrogen and progestin in patients with endometrial polyps (EP) and evaluate its clinical effect.Methods A total of 106 patients with EP treated in our hospital from July 2016 to March 2018 were selected as the research subjects.They were divided into control group (n=53) and treatment group (n=53) according to the random number table method.TCRP method was used in the control group.In the treatment group,estrogen and progestin method was added on the basis of the control group.The endometrial thickness,menstrual blood loss,estrogen and progesterone,adverse reactions and recurrence were compared between the two groups.Results The thickness of endometrium at 12 months after surgery in the treatment group was thinner than that in the control group,the pictorial blood loss assessment chart(PBAC) score was lower than that in the control group,and the differences were statistically significant (P<0.05).The estrogen level was lower and the progesterone level in the treatment group was higher compared with those in the control group,the differences were statistically significant (P<0.05).There were no statistical differences in the endometrial thickness,PBAC score,estrogen and progesterone levels of the two groups (P>0.05).The incidence and recurrence rate of prolonged menstrual period,irregular vaginal bleeding,breast distending pain in the treatment group were lower than those in the control group,and the differences were statistically significant (P<0.05).Conclusion TCRP combined with estrogen and progestin is effective in treating patients with EP,and it is safe and reliable.It can effectively reduce the thickness of the endometrium,promote menstrual recovery,and reduces adverse reactions and disease recurrence,which is worthy of reference.
蒋大梅. 子宫内膜息肉切除术联合雌孕激素在子宫内膜息肉患者中的应用[J]. 中国当代医药, 2020, 27(14): 124-126.
JIANG Da-mei. Application of transcervical resection of polyp combined with estrogen and progestin in patients with endometrial polyps. 中国当代医药, 2020, 27(14): 124-126.