Abstract：Objective To compare the application effect bewteen spinal anesthesia （SA）with No.26 LP needle and combined spinal-epidural anesthesia （CSEA）in cesarean section.Methods From January to June 2018，a total of 100 pregnant women who intended to undergo cesarean section in our hospital were selected as research objects and divided into SA group（50 cases）and CSEA group（50 cases）according to the random number table method.The SA group received SA with No.26 LP needle，and the CSEA group received CSEA.The onset time of anesthesia，sensory block recovery time，exercise block recovery time，excellent and good rate of anesthesia，blood pressure（systolic blood pressure，diastolic blood pressure），and heart rate before and after anesthesia and adverse reactions were compared bewteen the two groups.Results The onset time of anesthesia，sensory block recovery time and exercise block recovery time in the CSEA group were significantly shorter than those in the SA group，and the differences were statistically significant（P＜0.05）.The excellent and good rate of anesthesia in the CSEA group was 92.00%，compared with 90.00%in the SA group，and the difference was not statistically significant（P＞0.05）.There were no significant differences in systolic blood pressure，diastolic blood pressure and heart rate between the two groups before anesthesia（P＞0.05）.The systolic and diastolic blood pressures after anesthesia of the two groups were lower than those before anesthesia，and the differences were statistically significant（P＜0.05）.There was no significant difference in heart rate between the two groups before and after anesthesia （P＞0.05）.The systolic blood pressure after anesthesia in the SA group was higher than that in the CSEA group，and the difference was statistically significant（P＜0.05）.There were no significant differences in pressure and heart rate between the two groups after anesthesia （P＞0.05）.The total incidence rate of adverse reactions in the SA group was 4.00%，which was significantly lower than that in the CSEA group accounting for 26.00%，and the difference was statistically significant（P＜0.05）.Conclusions Both SA with No.26 LP needle and CSEA meet the anesthesia requirements of cesarean section.CSEA has a better time control，SA with No.26 LP needle has less impact on maternal circulation and fewer adverse reactions，which should be reasonably selected according to the situation.
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