Clinical application of Dexmedetomidine combined with proseal laryngeal mask airway in intracranial aneurysm embolization
LU Xian-qing1 ZHANG Jian-hua1 LIANG Jian-qun1 OUYANG Wen-bo1 HE Hui-jiao1 YIN Wan-chun2
1.Department of Anesthesiology,the First People′s Hospital of Zhaoqing City in Guangdong Province,Zhaoqing 526000, China;
2.Department of Cerebrovascular,the First People′s Hospital of Zhaoqing City in Guangdong Province,Zhaoqing 526000,China
Abstract：ObjectiveTo evaluate the efficacy of Dexmedetomidine combined with proseal laryngeal mask airway in intracranial aneurysm embolization.MethodsFrom February 2015 to February 2017,60 patients underwent intracranial aneurysm embolization in our hospital were selected and randomly divided into the control group and the study group,43 cases in each group.The study group was given Dexmedetomidine before anesthesia induction and continuous intravenous infusion until 20 minutes before the operation finished;the proseal laryngeal mask airway was given after anesthesia induction.The control group was given the same amount of normal saline,the proseal laryngeal mask airway was given after anesthesia induction.The heart rate(HR)and blood pressures(SBP and DBP)before injection(T0),before intubation(T1),before intubation(T2),1 min after intubation(T3),the moment of puncture(T4),the moment of embolization (T5),the end of the operation(T6),before extubation(T7),1 min after extubation(T8)were evaluated.The recovery time of spontaneous breathing,the time of pulling out the laryngeal mask and the recovery time of the directional force after stopping drug were recorded.The adverse reactions of patients with laryngeal mask airway,the amount of Remifentanil used in each case and the types and times of vasoactive drugs were recorded.ResultsThe level of HR,SBP and DBP in the study group at T3and the control group at T3,T5,T8was higher than that at T0(P＜0.05).The HR,SBP and DBP in the study group at T1,T2,T4,T6and T7and the control group at T2,T4,T6and T7was lower than that at T0(P＜0.05).The HR,SBP and DBP in the study group at T1to T8were significantly lower than that in the control group (P＜0.05).The recovery time and extubation time in the study group was significantly shorter than that in the control group,the incidence of adverse drug reactions during the operation,the dosage of Remifentanil,and vasoactive drugs use in the study group was significantly lower than that in the control group(P＜0.05).ConclusionDexmedetomidine combined with proseal laryngeal mask airway in the embolization of intracranial aneurysms,the patient′s hemodynamics is stable,the recovery time and extubation time is short,it is worth promoting.
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