Abstract:Objective To explore the clinical effect of glucocorticoids combined with Terbutaline in the treatment of acute exacerbation of chronic obstructive pulmonary disease (COPD).Methods 48 cases of COPD in our hospital from June 2013 to June 2015 were selected and divided into the experimental group and the control group according to the different treatment methods,24 cases in each group.The control group was treated with Terbutaline,the experimental group was treated with glucocorticoids on the basis of the control group.The treatment effect,oxygen partial pressure (PaO2),carbon dioxide partial pressure (PaCO2)and the incidence rate of adverse reaction was compared between the two groups.Results The total effective rate of the experimental group was 96%,which was higher than 70%of the control group,with significant difference (P<0.05).The level of PaO2in the experimental group after treatmentwas higher than that in the control group,the level of PaCO2in the experimental group after treatment was lower than that of the control group,with significant difference(P<0.05).The incidence rate of adverse reactions in the experimental group was 4.2%,which was lower than 25.0%in the control group,with significant difference (P<0.05).Conclusion Clinical effect of glucocorticoid combined with Terbutaline in the treatment of acute exacerbation of COPD is better,which can not only improve the level of PaO2and PaCO2,reduce the incidence rate of adverse reaction,but also can improve the quality of life of patients,it isworthy of clinical promotion and application.
邹小新;刘云云;凌学锋. 糖皮质激素与特布他林联合治疗慢性阻塞性肺疾病急性加重期的临床分析[J]. 中国当代医药, 2016, 23(27): 31-33.
ZOU Xiao-xin;LIU Yun-yun;LING Xue-feng. Clinical analysis of glucocorticoid combined with Terbutaline in the treatment of acute exacerbation of chronic obstructive pulmonary disease. 中国当代医药, 2016, 23(27): 31-33.