Abstract：ObjectiveTo explore the prevention effect for gastric and duodenal injury of Pantoprazole and Helicobacter pylori eradication therapy in elderly patients treated with Aspirin.Methods86 elderly patientswith peptic ulcer treated in our hospital from November 2014 to November 2015 and they were divided into control group and observation group in accordance with the admission order of even and odd-number.43 patients in control group were given Helicobacter pylori eradication therapy,while 43 patients in observation group were treated by Pantoprazole.The gastrointestinal injury,disease progression disease improvement situation in patients between two groups were compared.ResultsThe gastrointestinal injury rate and gastrointestinal injury degree in patients of observation group was obviously lower than that of control group respectively (P＜0.05).The disease progression,disease improvement situation of observation group were better than those of control group and the differences were statistically significant(P＜0.05).ConclusionPantoprazole can give more protection for stomach and duodenum of elderly patients treated with Aspirin than Helicobacter pylori eradication therapy,ofwhich the anti-acid treatmenteffect ismore ideal.
刘仁鹏. 泮托拉唑与根除幽门螺杆菌治疗对服用阿司匹林老年患者胃及十二指肠损伤的预防作用[J]. 中国当代医药, 2016, 23(34): 25-27.
LIU Ren-peng. Prevention effect for gastric and duodenal injury of Pantoprazole and Helicobacter pylori eradication therapy in elderly patients treated with Aspirin. 中国当代医药, 2016, 23(34): 25-27.