Abstract：ObjectiveTo investigate the infection status of Helicobacter pylori(Hp)in healthy people,analyze Hp infection-related influencing factors,and put forward countermeasures.MethodsA total of 235 healthy subjects who were given physical examination from January 2016 to January 2017 were randomly selected as subjects.Carbon-14 breath card test method was adopted for all health subjects to conduct Hp infection survey.At the same time,self-made questionnaire was used for the subjects to conduct daily situations.The observation indicators included the occurrence of Hp infection in healthy subjects,Hp infection-related factors,Hp infections in different age groups.ResultsA total of 115 patients with positive Hp were detected in 235 healthy subjects,accounting for 48.94%,the infection rate of Hp was 56.67%in the age group≥50 years old,which was significantly higher than that in the age group＜50 years old (35.29%)(P＜0.05);the infection rate of Hp was 65.93%in the drinking population,which was significantly higher than that of 26%in small drinking amount or non-drinking population(P＜0.05);the infection rate of Hp in smoking population was 60.39%,which was significantly higher than that of 27.16%in non-smokers(P＜0.05);the infection rate of Hp in patients with coronary heart disease and diabetes mellitus was significantly higher than that in patients without coronary heart disease and diabetes mellitus，the difference was statistically significant(P＜0.05).The infection rate of Hp in hypertensive population was 49.19%,and the infection rate was 50.81%in non-hypertensive population.There was no significant difference(P＞0.05).After a multivariate analysis,it was found that smoking(OR＝9.943,P＝0.045)and age≥50 years old(OR＝6.132,P＝0.039)were independent risk factors for Hp infection in healthy subjects.ConclusionHp infection in healthy people is closely related to poor living habits,history of diabetes mellitus,history of coronary heart disease and age.Smoking and age≥50 years old are independent risk factors for Hp infection in healthy people.
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