Observation of the effect of Amiodarone combined with Wenxin Granule in the treatment of coronary heart disease complicated with arrhythmia in elderly patients
JIANG Xiao-jie LIU Fang-peng TU Zhe-hong LI Shun-hui
No.1 Department of Cardiology,the Third Affiliated Hospital of Nanchang University in Jiangxi Province,Nanchang 330000,China
Abstract:Objective To observe the effect of Amiodarone and Wenxin Granule in the treatment of coronary heart disease and arrhythmia in elderly patients.Methods 85 cases of elderly patients with coronary heart disease and arrhythmia who were admitted to the outpatient in our hospital from June 2014 to July 2016 were selected as the study subjects.According to the random arrangement table method,the patients were divided into control group and observation group.42 patients in the control group were given Amiodarone for treatment,and 43 patients in the observation group was given Wenxin Granules+Amiodarone for treatment.Before and after treatment,the improvement of angina and arrhythmia(ventricular number,short array of ventricular speed)was observed before and after the treatment.The changes of hemodynamic indexes were measured in both groups,and the records of adverse events during treatment was compared.Results At the time of admission,the number of angina pectoris,times,the number of premature ventricular contraction,and the number of short array of ventricular fibrillation,there were no significant difference compared with the control group (P>0.05).After treatment,the indexes in the observation group respectively,the curative effect of arrhythmia and angina pectoris was better than that in the control group,with significant difference (P<0.05);upon admission,the hemodynamic index of plasma specific viscosity in the observation group,low shear viscosity,high shear viscosity fibrinogen,hematocrit were no significant differences compared with those in the control group,with significant difference (P>0.05).After treatment,the improvement of hemodynamic indexes in the observation group were all better than those in the control group,with significant difference (P<0.05);the incidence rate in the observation group was 9.3%,compared with 14.3%in the control group,there was no significant difference between the two groups (χ2=1.201,P>0.05).Conclusion After the combined treatment of amiodarone and wenxin granule for elderly patients with coronary heart disease and arrhythmia,the arrhythmia is improved,hemodynamics is recovered,and the adverse reactions are less.
江小杰;刘方鹏;涂颉洪;李顺辉. 胺碘酮联合稳心颗粒治疗老年冠心病合并心律失常的效果观察[J]. 中国当代医药, 2017, 24(28): 141-143.
JIANG Xiao-jie;LIU Fang-peng;TU Zhe-hong;LI Shun-hui. Observation of the effect of Amiodarone combined with Wenxin Granule in the treatment of coronary heart disease complicated with arrhythmia in elderly patients. 中国当代医药, 2017, 24(28): 141-143.