Abstract：Objective To investigate the application and clinical effect of perioperative multidisciplinary pain management combined with psychological intervention in modified radical mastectomy.Methods A total of 180 cases of breast cancer patients in the Second People′s Hospital of Neijiang from June 2017 to December 2018 were selected and divided into group A, group B and group C according to random number table method, 60 cases in each group.All patients were given general anesthesia through tracheal in tubation.Group A was given postoperative patient controlled intravenous analgesia (PCIA), group B was given nerve block combined postoperative PCIA, and group C was given psychological intervention combined nerve block and postoperative PCIA.The postoperative analgesia time was 48 h.Visual analogue score (VAS), PCIA pressing times and dosage of postoperative nonsteroidal analgesic of the three groups were observed at the first and third day after operation, Zung depression (SDS) and anxiety scale (SAS) were used to evaluate the psychological status of the three groups before operation and at the first and third day after operation, and the recent complications and hospital stay were observed among the three groups.Results There was no significant difference in preoperative VAS score among the three groups (P＞0.05).The VAS scores at the first and third days after operation in group C were lower than those in group A and group B, the differences were significant difference (P＜0.05).Pressing time of PCIA and dosage of postoperative nonsteroidal analgesic in C group were less than those in group A and group B, the differences were significant difference (P＜0.05).There were no significant differences in preoperative SDS and SDA scores among the three groups (P＞0.05).The SDS and SDA scores at the first and third days after operation in group C were lower than those in group A and group B, the differences were significant difference (P＜0.05).The total incidence of complications in group C was lower than that in group A and group B, the differences were significant difference (P＜0.05).The hospital stay in group B and group C was shorter than that in group A, the differences were significant difference (P＜0.05).Conclusion Perioperative multidisciplinary pain management combined with psychological intervention can alleviate psychological and physiological stress response in patients with modified radical mastectomy for breast cancer, relieve psychological pressure, improve analgesic effect after operation, and promote rehabilitation after operation.
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