摘要目的 观察宫腔镜对绝经后妇女子宫内膜厚度与子宫内膜疾病关系的诊断价值。方法 选取2019年10~12月南昌县莲塘镇本地户籍的1048例绝经后妇女进行阴道超声检查子宫内膜厚度,根据阴道超声检查结果分为两组,对子宫内膜<5 mm 与子宫内膜≥5 mm 的绝经后妇女进一步做宫腔镜检查,并与子宫内膜病理检查结果进行符合率分析,分析子宫内膜<5 mm 与子宫内膜≥5 mm 的绝经后妇女一般情况与子宫内膜疾病发病的差异,探讨子宫内膜厚度与子宫内膜病变的关系。结果 两组受试妇女的年龄、妊娠次数、绝经时间、体重指数、内膜厚度比较,差异有统计学意义(P<0.05);两组受试妇女单纯或复杂内膜增生、不典型内膜增生、慢性非特异性子宫内膜炎、内膜息肉、黏膜下肌瘤、内膜上皮瘤形成或内膜癌的发病率比较,差异有统计学差异(P<0.05);宫腔镜诊断的单纯或复杂内膜增生、不典型内膜增生、慢性非特异性子宫内膜炎、内膜息肉、黏膜下肌瘤、内膜上皮瘤形成或内膜癌与病理诊断的符合率分别为100.00%、85.71%、96.15%、96.56%、80.00%、75.00%。结论 绝经后妇女子宫内膜≥5 mm 的子宫内膜良恶性疾病的发病率增高,宫腔镜对其的诊断率与病理诊断的符合率超过75%,可作为绝经后妇女子宫内膜疾病的筛查方法。
Abstract:Objective To observe the diagnostic value of hysteroscopy on the relationship between endometrial thickness and endometrial diseases in postmenopausal women.Methods A total of 1048 postmenopausal women with local registration in Liantang Town of Nanchang County from October to December 2019 were selected for vaginal ultrasound to check the endometrial thickness and divided into two groups according to vaginal ultrasound results.Postmenopausal women with endometrium <5 mm and endometrium ≥5 mm were further subjected to hysteroscopy and analyzed with the endometrial pathology results,and the differences between the general condition of women and the incidence of endometrial diseases in postmenopausal women with endometrium <5 mm and endometrium ≥5 mm were analyzed to explore the relationship between endometrial thickness and endometrial lesions.Results The age,number of pregnancy,menopausal time,body mass index,and intimal thickness were compared between two groups,the differences were statistically significant (P<0.05).The incidence rates of simple or complex intimal hyperplasia,atypical intimal hyperplasia,chronic non-specific Heterosexual endometritis,endometrial polyps,submucosal fibroids,endometrial epithelioma formation or endometrial cancer were compared between two groups,the differences were statistically significant (P<0.05).Diagnostic rates of simple or complex endometrial hyperplasia,atypical endometrial hyperplasia,chronic nonspecific endometritis,endometrial polyps,submucosal fibroids,endometrial epithelioma formation or endometrial cancer in hysteroscope were compared with pathological diagnosis,their coincidence rates were 100.00%,85.71%,96.15%,96.56%,80.00%,75.00%,respectively.Conclusion The incidence of benign and malignant endometrial diseases in women with endometrium ≥5 mm is increased.The coincidence rate of hysteroscopy diagnosis and pathlogical diagnosis is more than 75%,which can be used as a screening method for endometrial diseases in postmenopausal women.
黄淑华. 宫腔镜在绝经后妇女子宫内膜厚度与相关疾病关系研究中的应用[J]. 中国当代医药, 2021, 28(5): 103-107.
HUANG Shu-hua. Application of hysteroscopy in the study of the relationship between endometrial thickness and related diseases in postmenopausal women. 中国当代医药, 2021, 28(5): 103-107.
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