Abstract：Colchicine is mainly used clinically for the treatment of gout,but its therapeutic dose is not much different from that of poisoning.Colchicine is rapidly absorbed after oral administration,and after poisoning,it will inhibit the mitosis of the cells,resulting in damage to multiple organ functions and even death.Colchicine has no effective antidote,early gastric lavage and symptomatic support treatment is necessary.This patient suffered from multiple organ failure after taking over-lethal dose of Colchicine.After continuous support therapy such as continuous renal replacement therapy,anti-infection,non-invasive ventilation,application of cell colony stimulating factor,blood product infusion,nutritional support,the patient successfully discharged.
陆丽丽； 孔德华； 王见斌； 张泽华. 致死量秋水仙碱中毒及救治1例[J]. 中国当代医药, 2020, 27(14): 195-197.
LU Li-li ； KONG De-hua； WANG Jian-bin ； ZHANG Ze-hua. A case report of lethal dose Colchicine poisoning and treatment. 中国当代医药, 2020, 27(14): 195-197.
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