Effect and safety of Lansoprazole in the treatment of duodenal ulcer bleeding
DING Kai YANG Hui
1.Outpatient Pharmacy，Balihu General Hospital of Jiujiang First People′s Hospital，Jiangxi Province，Jiujiang 332000，China;
2.Central Pharmacy，Jiujiang Third People′s Hospital，Jiangxi Province，Jiujiang 332000，China
Abstract：Objective To explore the effect and safety of Lansoprazole in the treatment of duodenal ulcer bleeding.Methods Sixty patients with duodenal ulcer bleeding admitted to our hospital from January 2016 to August 2018 were selected as the research objects，they were divided into control group and observation group according to random number table method，with 30 cases in each group.The control group was treated with Omeprazole （40 mg，with 0.9%saline，intravenous drip，bid），while the observation group was treated with Lansoprazole（30 mg，with 0.9%saline，intravenous drip，bid），after 5 days，the hemostasis time，abdominal pain stopping time，clinical efficacy and adverse reactions were compared between the two groups.Results There was no significant difference in hemostasis time，abdominal pain stopping time，total effective rate and total incidence of adverse reactions between the two groups （P＞0.05）.Conclusion Lansoprazole has the same effect as Omeprazole in the treatment of duodenal ulcer hemorrhage.Drugs can be selected according to the specific conditions.No serious adverse reactions occur.Lansoprazole is safe and worth popularizing.
丁凯；杨慧. 兰索拉唑治疗十二指肠溃疡出血的效果及安全性[J]. 中国当代医药, 2019, 26(6): 111-113.
DING Kai；YANG Hui. Effect and safety of Lansoprazole in the treatment of duodenal ulcer bleeding. 中国当代医药, 2019, 26(6): 111-113.
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