Diagnostic value of diffusion-weighted magnetic resonance imaging combined with magnetic resonance spectroscopy in the nature of prostatic lesions
GUO Zuo-liang1 MA Xing-can1 CHEN Ning1 MA Shu-hua2，3▲
1.Department of Radiology，Chaonan Minsheng Hospital of Shantou，Guangdong Province，Shantou 515144，China;
2.Department of Radiology，the First Affiliated Hospital of Medical College of Shantou University，Guangdong Province，Shantou 515041，China;
3.Key Laboratory，Medical Molecular Imaging in Guangdong Province，Medical College of Shantou University，Guangdong Province，Shantou 515041，China
Abstract：Objective To explore the diagnostic value of diffusion weighted magnetic resonance imaging （DWI）combined with magnetic resonance spectroscopy （MRS）in the nature and type of prostatic lesions.Methods Thirty-eight patients diagnosed as prostate cancer（PCa）in chaonan Minsheng hospital pf shantou from January 2016 to September 2018 were selected as observation group and 38 patients diagnosed as BPH as control group.DWI，MRS and DWI combined with MRS were performed in both groups.The difference of ADC value and （Cho+cre）/Cit value between the two groups was observed.The diagnostic results of DWI，MRS and DWI combined with MRS and the diagnostic coincidence rate were compared between the two groups.Results The ADC value of the observation group at 400 s/mm2was（0.86±0.28），significantly lower than that of the control group，the 800 s/mm2was（0.74±0.39），significantly lower than that of the control group，the differences were statistically significant（P＜0.001）.The Cho+cre/Cit value in the observation group was significantly higher than that in the control group，the difference was statistically significant（P＜0.001）.Pathological results of 76 patients：45 cases of prostate cancer and 31 cases of benign prostatic hyperplasia.Compared with pathological results，36 cases were diagnosed positive by DWI and 40 cases were negative，38 cases were diagnosed positive by MRS and 38 cases were negative，36 cases were diagnosed positive by DWI combined with MRS，and 30 cases were negative.The sensitivity，specificity and accuracy of combined DWI and MRS in the diagnosis of prostate cancer were 94.74%，92.11%and 92.11%，respectively，the sensitivity，specificity and accuracy of combined examination were significantly higher than those of DWI and MRS alone，the differences were statistically significant（P＜0.05）.Conclusion Both DWI and MRS can effectively diagnose PCa and BPH，can accurately distinguish between PCa and BPH patients，but MRS combined with DWI has higher diagnostic accuracy for prostate cancer，it can clearly show the relationship between the microstructure and metabolic level of prostate tissue.It is superior to DWI and MRS alone.It has important significance in clinical diagnosis and can provide important basis for early diagnosis.
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GUO Zuo-liang；MA Xing-can；CHEN Ning；MA Shu-hua. Diagnostic value of diffusion-weighted magnetic resonance imaging combined with magnetic resonance spectroscopy in the nature of prostatic lesions. 中国当代医药, 2019, 26(6): 92-95.
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