Abstract：Objective To study the clinical effect of finasteride combined with terazosin in treatment of benign prostatic hyperplasia.Methods A total of 120 patients with benign prostatic hyperplasia treated in our hospital from March 2015 to March 2017 were selected as the subjects.They were evenly divided into control group and treatment group by random grouping.In the control group,Terazosin was used,while in the treatment group,combination of Terazosin and Finasteride was adopted.The indexes of urodynamics including PVR,Qmaxand VMCC before and after therapy,improvement of prostate symptom and quality of life score,total effectiveness rate of BPH drug,drug-induced adverse reactions,time of urinary function return to normal and total time of medical treatment in the two groups were compared.Results In the treatment group,the improvement of PVR,Qmaxand VMCC in urodynamics,prostate symptom and quality of life before and after treatment were significantly more obvious than those in the control group,the differences were statistically significant(P＜0.05).The total effectiveness rate of BPH was 91.7%,higher than 70.0%in the control group,with a statistical difference(P＜0.05).The rate of drug-induced adverse reactions in the treatment group(5.0%)was less than that in the control group(18.3%),the difference was statistically significant(P＜0.05).The urinary function recovery time and the total duration of treatment were both shorter than those in the control group,the difference was statistically significant(P＜0.05).ConclusionFor BPH patients,application of finasteride can significantly improve the patient′s urinary function,control the symptoms,ameliorate patient′s quality of life,shorten the clinical treatment time,reduce the adverse reactions,and fundamentally improve the therapeutic effect of BPH.
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