Abstract:Objective To compare the effect of Propafenone and Amiodarone treating arrhythmia.Methods A total of 72 patients with arrhythmias treated in our hospital from February 2015 to December 2017 were selected.The patients were divided into control group and observation group using the random digital table method,and there were 36 cases in each group.The control group was treated with Propanone,while the observation group was treated with Amiodarone.Continuous treatment lasted for 5 weeks,the therapeutic effect,heart rate variability (HRV)parameter and drug safety were compared between the two groups.Results The total effective rate in the observation group was 97.2%,which was higher than that in the control group (77.8%)(P<0.05).The HRV parameter in the observation group was higher than that in the control group (P<0.05).The incidence of adverse reactions in the observation group was 5.6%,which was lower than that in the control group(22.2%)(P<0.05).Conclusion Amiodarone has more advantages compared with Propafenone in the treatment of arrhythmia.It can take into account both the clinical efficacy and the safety of medications.It can help patients correct their arrhythmia problems,and can be given priority when excluding medication contraindications.