甲氧明对全身麻醉下非心脏手术患者血压、心泵功能的影响

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摘要目的分析甲氧明对全身麻醉下非心脏手术患者术中血压、心泵功能的影响。方法选取2016年7月～2017年7月我院收治的164例全身麻醉非心脏手术患者作为研究对象，将其按照麻醉方法不同分为对照组（80例，微量持续泵注生理盐水）和观察组（84例，微量持续泵注甲氧明），观察两组患者术中血压、心泵功能的变化情况。结果在诱导后2 min、插管即刻以及插管后5 min，观察组的收缩压高于对照组，插管后1 min，观察组收缩压低于对照组,差异有统计学意义（P<0.05）；在诱导后2 min、插管后1 min，观察组舒张压低于对照组，插管后5 min，观察组舒张压高于对照组，差异有统计学意义（P<0.05）；插管后1、5、10 min两组患者的收缩压、舒张压水平变化与插管即刻内比较，差异有统计学意义（P<0.05）；诱导后2 min，观察组患者的LVEF、FS变化与对照组比较，差异有统计学意义（P<0.05）；插管即刻，观察组患者的LVEF、FS变化与对照组比较，差异有统计学意义（P<0.05）；插管后1 min，观察组LVEF变化与对照组比较，差异有统计学意义（P<0.05）；插管后5 min和10 min，对照组和观察组的LVEF、FS指标水平改变比较，差异无统计学意义（P>0.05）；插管后 1、5、10 min，两组患者的 LVEF、FS指标水平改变结果与插管即刻比较，差异有统计学意义（P<0.05）。结论甲氧明用于全身麻醉下非心脏手术患者术中，可以维持血压稳定，对心泵功能影响小，在临床麻醉中应用前景好。

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	查卫峰

关键词 ：甲氧明, 全身麻醉, 心泵功能

Abstract：Objective To analyze the effects of Methoxamine on the blood pressure and cardiac pump function in the patients undergoing non-cardiac surgery under general anesthesia.Methods From July 2016 to July 2017,164 patients undergoing non-cardiac surgery under general anesthesia treated in our hospital were selected as the subjects.According to different methods of anesthesia,they were divided into control group (80 cases,micro-sustained pump of normal saline)and observation group(84 cases,micro-sustained pump of Methoxamine).The changes in blood pressure and cardiac pump function during the operation were observed in both groups.Results The systolic blood pressure in the observation group was higher than that in the control group of 2 min after induction,immediately after intubation,and 5 minutes after intubation,at 1 min after intubation,the systolic blood pressure in the observation group was lower than that in the control group,the differences were statistically significant(P<0.05).At 2 min after induction and 1 min after intubation,the diastolic blood pressure in the observation group was lower than that in the control group,5 min after intubation,the diastolic blood pressure in the observation group was higher than that in the control group,the differences were statistically significant (P<0.05).At 1,5,10 min after intubation,there were statistically significant differences in the changes of diastolic blood pressure and systolic blood pressure compared within the intubation (P<0.05).At 2 min after induction,the changes of LVEF and FS were compared in the observation group than in the control group,the differences were statistically significant(P<0.05).Immediately after intubation,the changes of LVEF and FS in the observation group were significantly different from those in the control group (P<0.05).At 1 minute after intubation,the changes of LVEF in the observation group was compared with that in the control group,and the difference was statistically significant(P<0.05).At 5 min and 10 min after intubation,there was no statistically significant difference in LVEF and FS between the control group and the observation group (P>0.05).At 1 min,5 min,and 10 min after intubation,the results of changes in LVEF and FS levels within each of the two groups were compared with the results immediately after intubation,the differences were statistically significant(P<0.05).Conclusion The application of methoxamine in the patients undergoing non-cardiac surgery under general anesthesia can maintain blood pressure stability and have minor effect on the cardiac pump function,which has a good application prospect in clinical anesthesia.

Key words： Methoxamine General anesthesia Cardiac pump function

引用本文:

查卫峰. 甲氧明对全身麻醉下非心脏手术患者血压、心泵功能的影响[J]. 中国当代医药, 2018, 25(15): 74-76转80.
ZHA Wei-feng. Effects of Methoxamine on the blood pressure and cardiac pump function in the patients undergoing non-cardiac surgery under general anesthesia. 中国当代医药, 2018, 25(15): 74-76转80.

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http://dangdaiyiyao.com/CN/ 或 http://dangdaiyiyao.com/CN/Y2018/V25/I15/74

[1]	吴爱玲，杨勇，华薇，等.甲氧明对全身麻醉下择期进行非心脏手术患者全诱导期生命体征的影响[J].中国临床药理学杂志，2017，33（13）：1191-1193.
[2]	孟庆涛，孙倩，冷燕，等.盐酸甲氧明恒速泵注在老年冠心病患者行非心脏手术麻醉管理中的应用[J].武汉大学学报（医学版），2016，37（6）：1031-1034.
[3]	张凌，万磊，丁冠男.甲氧明持续输注对全麻复合硬膜外麻醉下开胸肺叶切除术中血流动力学的影响[J].临床和实验医学杂志，2017，16（9）：922-924.
[4]	汪懿，文怀昌，金孝岠，等.右美托咪定对全身麻醉下行非心脏手术老年患者术后早期认知功能影响的Meta分析[J].临床麻醉学杂志，2017，33（1）：45-51.
[5]	邹高锐，封享兰，范钧钊，等.氢化泼尼松与甲氧明对老年患者髋关节置换术中血流动力学的影响[J].山东医药，2017，57（37）：168-169.
[6]	杨亚琴，李淑霞.盐酸甲氧明及多巴胺对老年患者全麻诱导期间血流动力学及心脏泵功能影响的对比研究[J].河南医学研究，2017，26（1）：100-101.
[7]	刘继明，苏金华，佘乾斌，等.静脉预注甲氧明在重型颅脑外伤全身麻醉诱导期的应用[J].医药与保健，2017，25（2）：99-100.
[8]	陈龙，孙小婷，魏骐，等.持续输注甲氧明对胸腔镜手术麻醉期间低血压的防治效果[J].中华临床医师杂志（电子版），2016，10（3）：351-354.
[9]	赵艳丽，田丹丹.盐酸甲氧明和多巴胺对老年患者全麻诱导期间血流动力学及心脏泵功能的影响[J].广东医学，2016，37（10）：1551-1555.
[10]	赵东芳,杜艳梅,张晓莉.预注小剂量甲氧明防治老年患者腰硬联合麻醉后低血压的效果[J].浙江临床医学,2018，（2）：349-350.
[11]	王玉顺，曹远均，黄丽萍.甲氧明联合麻黄碱甲氧明对老年胃癌全麻后低血压的预防作用研究[J].河北医学，2017，23（10）：157-158.
[12]	卢盛位，吴小燕，谷艳娟，等.预注射与术中持续泵注甲氧明对剖宫产产妇血流动力学及新生儿血气指标的影响[J].贵阳医学院学报，2017，42（1）：109-112.
[13]	吕进.盐酸甲氧明对高龄患者全麻诱导期间心脏做功、心肌损伤及氧化应激反应的影响[J].海南医学院学报，2017，23（22）：164-165.
[14]	秦怀峰，宋建民，蒲新，等.小剂量静脉预注甲氧明预防老年患者全身麻醉诱导期低血压的疗效观察[J].重庆医学，2017，26（A02）：366-367.
[15]	林根，杨晓卿，蔡宇晶，等.甲氧明静脉预注预防腰硬联合麻醉下剖宫产低血压的效果及对血流动力学的影响[J].中国妇幼保健，2017，32（16）：3956-3958.