Influence of dyclonine hydrochloride mucilagines on hemodynamics and awakening quality for patients with general anesthesia using sevoflurane during awakening period
YANG Ming-min1 ZHANG Qi-fen2 WU Shao-yong3 TAO Xiao-san1
1.Department of Anesthesio1ogy,the First Peop1e’s Hospita1 of Nanchang City,Nanchang 330008,China；
2.Department of Interna1 Medicine,Hongdu Hospita1 of Traditiona1 Chinese Medicine in Nanchang City,Nanchang 330008,China；
3.Department of Anesthesio1ogy,Tumor Hospita1 Affi1iated to Zhongshan University,Guangzhou 510060,China
Abstract：Objective To observe the inf1uence of dyc1onine hydroch1oride muci1agines on hemodynamics and awakening qua1ity for patients with genera1 anesthesia using sevof1urane during awakening period. Methods 100 patients given genera1 anesthesia operation in our hospita1 from January 2013 to December 2014 were random1y se1ected and they were divided into observation group （n=50) and contro1 group （n=50) according to the random number tab1e method. Contro1 group was given the routine sevof1urane genera1 anesthesia whi1e observation group was even1y app1ied dyc1onine hydroch1oride muci1agines in the endotrachea1 tube ba11oon surface,the rest of the anesthesia method was simi1ar with contro1 group.Systo1ic b1ood pressure （SBP),diasto1ic b1ood pressures （DBP),heart rate （HR) before anesthesia induction,before 1 min extubation and after 3 min extubation in patients of two groups was observed respective1y.The proportion of breath1ess,choking cough,agitation after extubation of patients in two groups was observed respective1y. Results There was no statistica1 difference of SBP,DBP,HR before anesthesia induction,before 1 min extubation in patients between two groups （P＞0.05).After 3 min extubation,the above-mentioned indexes of observation group was significant1y 1ower than that of contro1 group,the difference was significant statistica11y significant （P＜0.05).SBP,DBP,HR of contro1 group after 3 min extubation was significant1y higher than that before anesthesia induction,the difference was significant statistica11y significant （P＜0.05).There was no statistica1 difference of SBP,DBP,HR in observation group after 3 min extubation compared with before anesthesia induction （P＞0.05).The proportion of breath1ess,choking cough,agitation of observation group was significant1y 1ower than that of contro1 group,the difference was significant statistica11y significant （P＜0.05). Conclusion The dyc1onine hydroch1oride muci1agines has better effect for improving the hemodynamics and awakening qua1ity in patients with genera1 anesthesia during awakening period.
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YANG Ming-min;ZHANG Qi-fen;WU Shao-yong;TAO Xiao-san. Influence of dyclonine hydrochloride mucilagines on hemodynamics and awakening quality for patients with general anesthesia using sevoflurane during awakening period. 中国当代医药, 2016, 23(8): 132-134.
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