佛山市社区人群糖皮质激素、非甾体抗炎药物胃肠损伤知晓率调查

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摘要目的了解社区人群对糖皮质激素、非甾体抗炎药物胃肠道损害的了解程度，为推广社区健康教育提供依据。方法采取整群抽样方法，对2014年10月佛山市顺德区伦教街道某大型小区的人群进行问卷调查，共调查1200人次，并对问卷调查结果进行统计分析。结果共发放调查问卷1200份，回收有效调查表1168份，其中男性560份，女性608份。所有有效调查人群中，曾服用糖皮质激素者14例（1.2％），无长期服用＞1个月者。知晓糖皮质激素胃肠损伤者62例（5.3％），其中男性23例（4.1％），女性39例（6.4％）。不同性别的糖皮质激素胃肠损伤知晓率比较，差异无统计学意义（P＞0.05）。高学历人群中糖皮质激素胃肠损伤知晓者45例（9.2％），低学历人群知晓者17例（2.5％）。不同学历的糖皮质激素胃肠损伤知晓率比较，差异有统计学意义（P＜0.05）。所有有效调查人群均曾服用非甾体抗炎药，长期服用＞1个月者42例（3.5％），主要为防治心脑血管疾病、治疗骨关节疾病。知晓非甾体抗炎药物胃肠损伤者85例（7.2％），其中男性34例（6.1％），女性51例（8.4％），不同性别的非甾体抗炎药物胃肠损伤知晓率比较，差异无统计学意义（P＞0.05）。高学历人群知晓NSAIDs胃肠损伤者64例（13.1％），低学历人群知晓者21例（3.1％）。不同学历的非甾体抗炎药物胃肠损伤知晓率比较，差异有统计学意义（P＜0.05）。结论相对于糖皮质激素，社区人群非甾体抗炎药物使用率较高，部分中老年人需长期服用；相对予高学历人群，低学历人群的胃肠损害知晓率较低，需对患者加强健康宣传教育，避免胃出血、消化性溃疡、消化道穿孔等副作用。

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关键词 ：糖皮质激素, 非甾体抗炎药物, 问卷调查, 糜烂性胃炎, 消化性溃疡

Abstract： Objective To get known the awareness degree of gastrointestinal injury caused by glucocorticoid and nonsteroidal anti-inflammatory drugs（NSAIDs）by community population in order to provide a basis for popularizing community health education. Methods By cluster sampling in October 2014,1200 people were surveyed of some community,Lunjiao street of Shunde district in Foshan city.The outcome of these surveyed questionnaire was statistically analyzed. Results There were 1200 questionnaires delivered in total,and effective ones were 1168 in recycle.In male,there were 560 cases,while the rest was female.Among these effective cases,14 people once were given glucocorticoid,accounted for 1.2％.No one was given the glucocorticoid more than one month.There were 62 people who knew the gastrointestinal injury caused by glucocorticoid,and the awareness rate was 5.3％,the males were 23 case（4.1％）, and the female were 39 cases（6.4％）.There was no significant difference in the awareness rate of the gastrointestinal injury caused by glucocorticoid between the different gender（P＞0.05）.Among these 62 people,45 ones from high educational background knew the gastrointestinal injury caused by glucocorticoid,and the awareness rate was 9.2％,while in low educational background,there were only 17 ones,and the awareness rate was 2.5％.There was significant difference in the awareness rate of the gastrointestinal injury caused by glucocorticoid between the different educational background（P＜0.05）.Among these effective surveyed people,all of them was given NSAIDs.There were 42 people who took these drugs for more than one month,accounted for 3.5％.These NSAIDs were mainly used for prevention and treatment of cardiovascular and cerebrovascular diseases and osteoarticular diseases.There were 85 people who knew the gastrointestinal injury caused by NSAIDs,and the awareness rate was 7.2％,the male were 34 cases（6.1％）,and the female were 51 cases（8.4％）.There was no significant difference in the awareness rate of the gastrointestinal injury caused by NSAIDsbook=158,ebook=164between the different gender（P＞0.05）.Among high educational background population,there were 64 ones who knew the gastrointestinal injury caused by NSAIDs,and the awareness rate was 13.1％.In low educational background,21 people knew that,and the awareness rate was 3.1％. There was significant difference in the awareness rate of the gastrointestinal injury caused by by NSAIDs between the different educational background（P＜0.05）. Conclusion Compared with glucocorticoid,usage rate of NSAIDs in community population is higher,and some of the elder need to take for a long time.In comparison with high educational background people,the awareness rate of gastrointestinal injury in people of low educational background is lower,which needs to intensify health promotion and education aiming at avoiding side effects like gastrorrhagia,peptic ulcers and gastrointestinal perforation,etc..

Key words： Glucocorticoid Non-steroidal anti-inflammatory drugs Questionnaire survey Erosive gastritis Peptic ulcer

基金资助:广东省佛山市科技局医学类科技攻关项目（201308278）

引用本文:

邓亮;范昭豪;李淑芳;劳武健. 佛山市社区人群糖皮质激素、非甾体抗炎药物胃肠损伤知晓率调查[J]. 中国当代医药, 2016, 23(2): 157-160.
DENG Liang;FAN Zhao-hao;LI Shu-fang;LAO Wu-jian. Investigation of awareness rate of gastrointestinal injury caused by glucocorticoid and non-steroidal anti-inflammatory drugs in community population in Foshan city. 中国当代医药, 2016, 23(2): 157-160.

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http://dangdaiyiyao.com/CN/ 或 http://dangdaiyiyao.com/CN/Y2016/V23/I2/157

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