Clinical study of painless endoscopic injection of hemostasis combined with high dose Esomeprazole in the treatment of peptic ulcer bleeding
ZHOU Lei1, SU Chu-xia1, LI Chun-nan1, DING Zi-le2
1.Department of Gastroenterology,the People′s Hospital of Chao an District in Chaozhou City,Guangdong Province,Chaozhou 515638,China; 2.Department of Anesthesiology,the People′s Hospital of Chao an District in Chaozhou City,Guangdong Province,Chaozhou 515638,China
Abstract:Objective To investigate the clinical efficacy of painless endoscopic injection of hemostasis combined with high-dose Esomeprazole in the treatment of peptic ulcer bleeding.Methods 90 case of peptic ulcer bleeding patients in our hospital from March 2015 to February 2017 were selected and randomly divided into group A(30 patients with high-dose Esomeprazole),group B(painless endoscopic injection of hemostatic combined with conventional doses of Esomeprazole,30 patients),group C(painless endoscopic injection of hemostasis combined with high-dose Esomeprazole treatment,30 cases),The three groups of stop bleeding time,length of stay,hospital costs and re-bleeding and surgery were compared.Results The time of stop bleeding,hospitalization and hospital costs were higher in group A than those in group B and group C.The time of stop bleeding,hospitalization and hospital costs in group B were higher than those in group C(P<0.01).The rate of rebleeding was higher in group A than that in group C,and the rate of operation was higher than that of group B and C(P<0.05).Conclusion Painless Endoscopic injection of hemostatic combined with high doses of esomeprazole in patients with peptic ulcer bleeding treatment can improve the hemostatic effect,reduce the incidence of rebleeding.
周磊, 苏楚霞, 李淳南, 丁字乐. 无痛内镜下注射止血联合大剂量埃索美拉唑治疗消化性溃疡出血的临床研究[J]. 中国当代医药, 2017, 24(25): 20-22.
ZHOU Lei, SU Chu-xia, LI Chun-nan, DING Zi-le. Clinical study of painless endoscopic injection of hemostasis combined with high dose Esomeprazole in the treatment of peptic ulcer bleeding. 中国当代医药, 2017, 24(25): 20-22.
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