Abstract：ObjectiveTo explore the effect of multi-point puncture plus local hypothermia drainage(MPPLHD)treating the elder severe hypertensive intracerebral hemorrhage.MethodsFrom June 2011 to December 2016,81 elder patients with severe hypertensive intracerebral hemorrhage were selected as object and they were divided into MPPLHD group(n=37)and conventional craniotomy group (CC group,n=44)according to the patient situation and family wishes.In CC group,removal of hematoma by standard large bone flap craniotomy was adopted.MPPLHD group was treated with MPPLHD.Hematoma clearance rate,intracranial pressure,brain edema with considerable increment at the third,fifth,seventh day,blood NSE concentration,neurological deficit score(NDS)and activity of daily living(ADL)score were compared between the two groups.ResultsThe first hematoma evacuation rate in MPPLHD group was lower than that in the CC group (P＜0.05）,the hematoma evacuation rate after the third,fifth day operation in MPPLHD group was higher than those in CC group (P＜0.05).Brain edema with considerable increment at the third,fifth,seventh day and blood NSE concentration in MPPLHD group were obviously lower than that of CC group(P＜0.05).After 28 days,3 and 5 months operation,NDS and ADL score in MPPLHD group were better than those of CC group (P＜0.05).ConclusionMPPLHD can effectively remove hematoma and reduce the loss of postoperative nerve function.It is an effective method for the treatment of elder severe hypertensive cerebral hemorrhage.
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