APPlication value of combined detection of homocysteine,hyPersensitive C- reactive Protein and D-dimer in the diagnosis and Prognosis of stroke
LIN Yu-feng1 HUANG Xing-hong2
1.C1inica1 Laboratory,Peop1e's Hospita1 of Yangjiang City in Guangdong Province,Yangjiang 529500,China;
2.Departmen of Obstetrics and Gyneco1ogy,Peop1e's Hospita1 of Yangjiang City in Guangdong Province,Yangjiang 529500,China
Abstract:Objective To exp1ore the app1ication va1ue of combined detection of homocysteine (Hcy),hypersensitive C-reactive protein (hs-CRP) and D-dimer (DD) in the diagnosis and prognosis of stroke. Methods 224 cases of stroke (96 cases of cerebra1 hemorrhage,128 cases of cerebra1 infarction) from May 2013 to September 2014 in our hospita1 were se1ected as the research object,115 hea1thy persons in the same period were se1ected as the hea1thy contro1 group.The 1eve1 of Hcy,hs-CRP and DD in the each group was compared. Results The 1eve1 of Hcy,hs-CRP and DD in the stroke group was higher than that in the hea1thy contro1 goup,with significant difference (P<0.05).The 1eve1 of Hcy,hs-CRP and DD in the cerebra1 hemorrhage group and the cerebra1 infarction group was higher than that in the hea1thy contro1 goup,with significant difference (P<0.05).The positive rate of combined detection of Hcy,hs-CRP and DD in the stroke group was 91.5%,which was higher than 3.5% in the hea1thy contro1 goup,with significant difference (P<0.05).The positive rate of Hcy,hs-CRP and DD in the stroke group was higher than that in the hea1thy contro1 goup,with significant difference (P<0.05). Conclusion Hcy 1eve1 is an important predictor of stroke,combined detection of Hcy,hs-CRP and DD is he1pfu1 for ear1y diagnosis and treatment of stroke,and which a1so has important c1inica1 va1ue in judging prognosis.
林裕锋; 黄幸红. 同型半胱氨酸、超敏C-反应蛋白和D-二聚体联合检测在脑卒中诊断和预后判断中的应用价值[J]. 中国当代医药, 2016, 23(9): 19-21.
LIN Yu-feng;HUANG Xing-hong. APPlication value of combined detection of homocysteine,hyPersensitive C- reactive Protein and D-dimer in the diagnosis and Prognosis of stroke. 中国当代医药, 2016, 23(9): 19-21.
Sa1omaa V,Stinson V,Kark JD,et al.Association of fibrino1ytic parameters with er1y atherosc1erosis.The ARIC Study Atherosc1erosis Risk in Communities Study[J].Cir cu1ation,1995,91(2):284-290.