Abstract：Objective To investigate the effect of atorvastatin in the treatment of cerebra1 infarction.Methods 140 cases of cerebra1 infarction in our hospita1 from December 2012 to December 2014 were random1y divided into the contro1 group（70 cases）and the observation group（70 cases），the contro1 group was given routine treatment，the observation group was treated with atorvastatin on the basis of conventiona1 therapy，the 1eve1 of hs-CRP，MMP-9，TC，LDL-C and NIHSS score between two groups were compared.Results The tota1 effective rate of the observation group was 94.28%，significant1y higher than 82.86%in the contro1 group，with statistica1 difference（P＜0.05）；after treatment，the 1eve1 of MMP-9，hs-CRP，TC and LDL-C in two groups was different degrees of dec1ine respective1y and the observation group was significant1y 1ower than that of the contro1 group respective1y，with statistica1 difference（P＜0.05）；after treatment，the NIHSS score of the observation group was significant1y 1ower than that of the contro1 group with statistica1 difference（P＜0.05）. Conclusion Atorvastatin can reduce the cerebra1 infarction patients with hs-CRP，MMP-9，TC and LDL-C 1eve1，a11eviate cerebra1 infarction patients with inf1ammatory reaction，improve the neuro1ogic function in patients.It is worthy of c1inica1 popu1arization and app1ication.
汪勇. 阿托伐他汀治疗脑梗死的临床效果[J]. 中国当代医药, 2016, 23(14): 115-117.
WANG Yong. Clinical effect of atorvastatin in the treatment of cerebral infarction. 中国当代医药, 2016, 23(14): 115-117.
Song IU，Kim YD，Kim JS，et al.Can high-sensitivity C-reactive protein and p1asma homocysteine 1eve1s independent1y predict the prognosis of patients with functiona1 disabi1ity after first-ever ischemic stroke？［J］.Eur Neuro1，2010，64（5）：304-310.
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