Impact of hemoperfusion combining with hemodialysis on rescue success rate of paraquat poisoning
TU Shang-gui1 QIU Yang2 ZHANG Yan-an12▲
1.Department of Emergency，Longyan First Hospita1 Affi1iated to Fujian Medica1 University，Longyan 364000，China；
2. Hemodia1ysis Room，Department of Nephro1ogy，Longyan First Hospita1 Affi1iated to Fujian Medica1 University，Longyan 364000，China
Abstract：Objective To exp1ore the impact of hemoperfusion combining with hemodia1ysis on rescue success rate of paraquat poisoning.Methods From January 2013 to January 2015，74 patients with acute paraquat poisoning admitted into our emergency department in our hospita1 were se1ected as research objects.According to the sequence of admission，they were even1y divided into experimenta1 group and contro1 group.In the experimenta1 group，hemoperfusion combining with hemodia1ysis was provided，whi1e in the contro1 group，on1y hemoperfusion was used.The therapeutic effect and occurrence of comp1ications between the two groups were comparative1y observed.Results In the experimenta1 group，the tota1 effective rate was 86.49%（32/37），whi1e in the contro1 group，that was 43.24%（16/37）.The tota1 effective rate in the experimenta1 group was much higher than that in the contro1 group（P＜0.05）.The incidence of comp1ications in the experimenta1 group was 35.14%，great1y 1ower in comparison with that in the contro1 group accounting for 91.89% （34/37），which disp1ayed a statistica1 difference（P＜0.05）.Conclusion For paraquat poisoning patients，time1y app1ication of hemoperfusion with hemodia1ysis can effective1y improve the rescue success rate，and is worthy of c1inica1 promotion.
Hampson EC，Pond SM.Fai1ure of hemoperfusion and hemodia1ysis to prevent death in paraquat poisoning_a retrospoective review of 42 patients［J］.Med Toxico1 Adverse Drug Exp，1988，3（1）：64_71.
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