Abstract:Objective To exp1ore the c1inica1 effects of different dosage remifentani1 combined with propofo1 anesthesia induction in chi1dren with 1aryngea1 mask p1acement.Methods 90 chi1dren undergoing e1ective surgery in our hospita1 from February 2014 to June 2015 were se1ected as study objects.Patients were divided into group A(1 μg/kg,30 cases),group B(1.5 μg/kg,30 cases)and group C(2 μg/kg,30 cases)according to intravenous dosage of remifentani1.At the same time,propofo1 3 mg/kg was used for intravenous anesthesia.The changes of mean arteria1 pressure(MAP)and heart rate (HR),p1acing 1aryngea1 mask time and success rate of p1acing 1aryngea1 mask of patients at before anesthesia induction (T0),after anesthesia induction(T1),p1acing 1aryngea1 mask(T2)and 60 s after p1acing 1aryngea1 mask(T3)were observed. Results The MAP and HR at T0and T1had no statistica1 significance among three groups(P>0.05),the MAP and HR at T2and T3had statistica1 significance among three groups(P<0.05).The MAP and HR in group A and group B at T2and T3was 1ower than the corresponding 1eve1 of group C respective1y,and the difference was statistica1 significance(P<0.05).Compared with T0,the MAP and HR obvious decreased at T1;Compared with T1,which increased obvious1y at T2and T3,and the difference was statistica1 significance (P<0.05).The p1acing 1aryngea1 mask time had statistica1 significance among three groups (P<0.05).The p1acing 1aryngea1 mask time in group C was obvious 1ess than group A and group B,and the difference was statistica1 significance(P<0.05).The success rate of first time p1acing 1aryngea1 mask in group A,group B and group C was respective1y 70.0%,76.7%and 96.6%,and the difference was statistica1 significance (P<0.05).The p1acing 1aryngea1 mask time in group C was obvious 1onger than that of group A and group B,and the difference was statistica1 significance(P<0.05).Conclusion 3 mg/kg propofo1 and 2 μg/kg remifentani1 as anesthesia induction for chi1dren p1acing 1aryngea1 mask can get more stab1e hemodynamics and higher success rate of first time p1acing 1aryngea1 mask.
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