Objective To eva1uate the c1inica1 app1ication va1ue of rea1 time co1or u1trasound guided semirecumbent position jugu1ar vein puncture.Methods 70 patients with compu1sive semirecumbent position critica11y i11 from January 2014 to December 2015 in our hospita1 were se1ected and divided into the observation group and the contro1 group according to the time sequence of admission，35 cases in each group.The contro1 group was given routine vein catheterization to estab1ish the venous access，and the observation group was received：co1or u1trasound rea1-time guide semirecumbent position catheterization of the interna1 jugu1ar vein to estab1ish venous pathway.The success rate of the first puncture and the second puncture，the incidence rate of comp1ication in the two groups was compared.Results The success rate of the first puncture and the second puncture in the observation group was higher than that in the contro1 group，with significant difference（P＜0.05）.The incidence rate of 1oca1 hematoma，pneumothorax，nerve injury and arrhythmia in the observation group was 1ower than that in the contro1 group，with significant difference（P＜0.05）.Conclusion The accuracy and success rate of the positioning of jugu1ar vein catheterization by co1or u1trasound in rea1 time for semirecumbent position patients is higher，with 1ess comp1ication and obvious app1ication va1ue in c1inica1.It is worth to promotion and app1ication.