Abstract:Objective To explore the effect of Bifidobacterium combined with Kangfuxin liquid in the treatment of severe ulcerative colitis.M ethods 150 severe ulcerative colitis patients from December 2012 to December 2015 in our hospitalwere selected and randomly divided into group A,group B and group C,50 cases in each group.On the basis of hormone therapy,group A was treated with Bifidobacterium tetravaccine tablets,group B was treated with Kangfuxin liquid,group C was treated with Bifidobacterium tetravaccine tablets and Kangfuxin liquid.Therapeutic effect,the symptom disappeared time of diarrhea and hematochezia,the normal time of ESR and CRP recovery,anifestation of colonoscopyand the condition of adverse reaction among the three groupswas compared.Results The total effective rate in group C was higher than that in group A and group B,with significant difference(P<0.05).The total remission rate ofmucosal lesion under colonoscopy in group C was higher than that in group A and group B,with significant difference (P<0.05). The symptom disappeared time of diarrhea and hematochezia,the normal time of ESR and CRP recovery the normal time of ESR and CRP recovery in group C was shorter than that in group A and group B,with significant difference(P<0.05).Conclusion On the basis of using hormone,combined with Bifidobacterium and Kangfuxin liquid in the treatment severe ulcerative colitis can improve clinical symptoms,promotemucosal repair,with less adverse effects and isworth to popularize apply in clinical.
李远洪. 双歧杆菌联合康复新液治疗重度溃疡性结肠炎的疗效观察[J]. 中国当代医药, 2016, 23(20): 138-140.
LIYuan-hong. Effect observation of Bifidobacterium combined w ith Kangfuxin liquid in the treatment of severe ulcerative colitis. 中国当代医药, 2016, 23(20): 138-140.