Abstract:ObjectiveTo observe the clinical effect of Kangfuxin Liquid in the treatment ofmild tomoderate inflammatory bowel disease.MethodsSixty patientswithmild tomoderate IBD treated in our department from June 2012 to June 2015 were randomly divided into two groups.The treatment group was treated by Kangfuxin Liquid of 10 ml every time for three times a day,at the same time,Mesalazine Sustained-Release Tablets of 1 g every time for four times a day and Compound Glutamin Entersoluble Capsules of 2 pills every time for three times a day.Control group was given Mesalazine Sustained-Release Tablets of 1 g every time for four times a day and Compound Glutamin Entersoluble Capsules 2 pills every time for three times a day.Two groups were given 4 weeks treatment as a course.After three courses of treatment,the treatment effectwas compared by reviewing the colonoscopy and the corresponding score.ResultsThe total effective ratewas 93.3%in the treatment group and 73.3%in the control group.The treatment group was significantly higher than the control group,and the difference was statistically significant(P<0.05).The improvement of Mayo score in UC patientswas better than that of the control group (P<0.05).The improvement of Best CDAI score in CD patientswas better than that of the control group(P<0.05).ConclusionKangfuxin Liquid in the treatment ofmild to moderate inflammatory bowel disease has a exact therapeutic effect and it isworthy of promotion.
Lang SM,Stratakis DF,Heinzlmann M,etal.Molecular screening of patients with long standing extensive ulcerative colitis:detection of p53 and Ki-ras mutations by single strand conformation polymorphism analysis and differential hybridisation in colonic lavage fluid[J].Gut,1999,44(6):822-825.
Nachman RJ,Holman GM.Myotropic insect neuropeptide families from the cockroach Leucophaeamaderae:structure activity relationships.[J].ACSSymp Ser,1991,(453):194-214.
[12]
Predel R,Kellner R,Rapus J,et al.Isolation and structural elucidation of eight kinins from the retrocerebral complex of the American cockroach,Periplaneta americana[J].Regul Pept,1997,71(3):199-205.
[13]
Tomas A,Futter CE,Eden ER.EGF receptor trafficking:consequences for signaling and cancer[J].Trends Cell Biol,2014,24(1):26-34.
[14]
Arkhipov A,Shan Y,DasR,etal.Architecture andmembrane interactions of the EGF receptor[J].Cell,2013,152(3):557-569.