Abstract：Objective To explore the improvement of neurologic function impairment and themechanism for Edaravone in patientswith transient ischemic attack （TIA）. Methods 120 patientswith TIA admitted to the department of neurology in our hospital and met the inclusion criteria from April 2015 to April 2016 were selected and divided into the highrisk group，themedium risk group and the low risk group according to risk stratification of ABCD2，40 cases in each group.Each subgroup was divided into group A （high risk group treated with Edaravone），group B （medium risk group treated with Edaravone），group C（low risk group treated with Edaravone），group D（high risk group treated with the basis for treatment），group E（medium risk group treated with the basis for treatment），group F（low risk group treated with the basis for treatment），20 cases in each group.The score of NIHSSand the score of daily life activities ability among each group was compared in attack，after treatment at the 3rddays，14thdays，28thdays and the incidence rate of adverse reaction was recorded.Results The score of NIHSSafter treatment at the 3rddays，14thdays，28thdays in group C and group F was lower than that in group A，group B，group D，group E，the score of NIHSSafter treatment at the 3rddays，14thdays，28thdays in group A was lower than that in group D，the score of NIHSS after treatment at the 3rddays，14thdays，28thdays in group B was lower than that in group E，with significant difference （P＜0.05）.The score of NIHSS after treatment at the 3rddays，14thdays，28thdays in each group were all decreased，and the difference was statistically significant（P＜0.05）.The score of daily life activities ability after treatment at the 3rddays，14thdays，28thdays in group C and group F was higher than that in group A，group B，group D，group E，the score of daily life activities ability after treatment at the 3rddays，14thdays，28thdays in group A was higher than that in group D，the score of daily life activities ability after treatment at the 3rddays，14thdays，28thdays in group B was higher than that in group E，with significant difference （P＜0.05）.The score of daily life activities ability after treatment at the 3rddays，14thdays，28thdays in each group were all increased，and the difference was statistically significant（P＜0.05）.There was no obvious adverse reaction in each group.Conclusion Edaravone can improve the neurologic function impairment of high，moderate risk groupswith TIA，and the security is higher.
刘静静. 依达拉奉对短暂性脑缺血的干预效果观察[J]. 中国当代医药, 2016, 23(29): 107-110.
LIU Jing-jing. Intervention observation and research of the Edaravone in transient ischem ic attack. 中国当代医药, 2016, 23(29): 107-110.
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