Abstract：Objective To explore the emergency treatmentof severe asthmawith respiratory failure and itseffect.Methods From January 2012 to December 2015，100 cases of patientswith severe asthma and respiratory failure were selected as the subjects of this study.The patientswere randomly divided into the control group and the observation group by taking the digital random tablemethod，50 cases in each group.The control group was given routine treatment，the observation group was treated with noninvasive positive pressure ventilation at the same time.The carbon dioxide partial pressure （PaCO2），oxygen partial pressure（PaO2），pH value，respiratory rate（RR）before and after treatmentwere compared between two groups，and the time of hospital stay and death were compared between two groups.Results After treatment，PaCO2and RR in two groupswere significantly decreased （P＜0.05），PaO2，pH value in two groupswere significantly increased （P＜0.05），and the indexes were compared between two groups，with the statisticant differences（P＜0.05）.Compared with the control group，the time of hospital stay in the observation group was significantly shorter（P＜0.05）.There were no deaths in the observation group，the rate of death in the control group was 4%，the difference was not statistically significant（P＞0.05）.Conclusion In the emergency treatment of patientswith severe asthma and respiratory failure，the implementation of noninvasive positive pressure ventilation can effectively improve the patient′s blood oxygen condition，correct the hypoxia and acidosis state，it is help to reduce the patient′smortality.
张洪林. 急诊治疗严重哮喘呼吸衰竭的方法及效果初步研究[J]. 中国当代医药, 2016, 23(26): 25-27.
ZHANG Hong-lin. Prelim inary study on the method and effect of emergency treatment of severe asthma with respiratory failure. 中国当代医药, 2016, 23(26): 25-27.
Shlamovitz GZ，Hawthorne T.Intravenous ketamine in a dissociating dose as a temporizing measure to avoid mechanical ventilation in adult patientwith severe asthma exacerbation［J］.JEmerg Med，2011，41（5）：492-494.
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