Effect analysis of laparoscopic splenectom y in the treatment of idiopathic thrombocytopenic purpura
YIBo CHEN Xun TANG Cai-xi
Department of Hepatic,Biliary and Pancreatic Surgery,Zhuzhou Hospital Affiliated to Xiangya Medical College of Central South University,Zhuzhou 421007,China
Abstract:Objective To explore the effect of laparoscopic splenectomy in the treatment of idiopathic thrombocytopenic purpura.Methods 40 patientswith idiopathic thrombocytopenic purpura from January 2010 to January 2015 in our hospitalwere selected and randomly divided into the trial group and the control group,20 cases in each group.The control group was treated with traditional splenectomy,the trial group was treated with laparoscopic splenectomy.The therapeutic effect,the amount of intraoperative blood loss,operative time,length of hospital stay,recurrence rate and the incidence rate of complication in the two groups was compared.Results There was no significant difference in the total effective rate between the two groups(P>0.05).The amount of intraoperative blood loss in the trial group was less than that in the control group,the length of hospital stay in the trial group was shorter than that in the control group,the total amount of fluid infusion and the total hospital costs in the trial group was less than that in the control group,with significant difference(P<0.05).There was no significant difference in the operative time between the two groups(P>0.05).There was no significant difference in the recurrence rate between the two groups(P>0.05).The incidence rate of complication in the trial group was 15.0%,which was lower than 40.0%in the control group,with significant difference(P<0.05).Conclusion Laparoscopic splenectomy in the treatment of idiopathic thrombocytopenic purpura can effectively improve the patient's symptoms,operation is safe,with low recurrence rate,fewer complications,it has important clinical significance.
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