Abstract:Objective To explore the clinical effects of one stage simple posterior approach in the treatment of thoracic and lumbar spine tuberculosis.Methods 63 patients with thoracic and lumbar spine tuberculosis in our hospital from March 2008 to October 2013 were selected as study object.All patients were used one stage simple posterior debridement,interbody fusion and screw rod internal fixation,anti tuberculosis treatment before operation and after operation were used.The clinical effects were evaluated according to pain visual analogue scale(VAS),Cobb angle correction,recovery of neurological function,prognosis of tuberculosis and bone graft fusion.Results All patients were successfully completed surgery,and the operation time and bleeding during operation was respectively(210.0±45.8)min and(550± 139)ml.63 patients were followed up,and the following up time and bone graft fusion time was respectively(31.0± 12.1)months and(5.0±1.3)months.No patients appeared complications of incision infection,chronic sinus formation and infectious meningitis.No recurrence of tuberculosis was seen at the last follow-up.The neurological function of 21 patients with neurological dysfunction improved 1 to 2 grades;VAS score reduced from(7.8±0.7)scores before operation to (1.9±0.3)scores after operation(F=21.4,P<0.05);Cobb angle was corrected from(27.6±5.3)°before operation to(9.8± 4.3)°at the last follow-up(F=83.6,P<0.05)and the last correct rate was 63.5%.Conclusion Using one stage simple posterior debridement,interbody fusion and screw rod internal fixation in treating short segment and circumscribed lesions of thoracic and lumbar tuberculosis can get good treatment effects.
刘汉辉;李辉;刘鹄. 一期单纯经后路手术治疗胸腰椎结核的临床效果分析[J]. 中国当代医药, 2016, 23(31): 63-66转73.
LIU Han-hui;LI Hui;LIU Hu. Clinical effects analysis of one stage simple posterior approach in the treatment of thoracic and lumbar spine tuberculosis. 中国当代医药, 2016, 23(31): 63-66转73.
Jiang T,Zhao J,He M,et al.Outcomes and treatment of lumbosacral spinal tuberculosis:a retrospective study of 53 patients[J].PLoS One,2015,10(6):180-185.
BezerM,KueukdurmazF,AydinN,etal.Tuberculousspondylitis of the lumbosacral region:disabling low back pain syndrome caused by internal disc long-term follow-up of patients treated by chemotherapy,transpedicular drainage,posterior instrumentation,and fusion[J].J Spinal Disord Tech,2015,18(5):425-429.
Lee CK,Vessa P,Lee JK.Chronic disabling low back pain syndrome caused by internal disc derangements.The results of disc excision and posterior lumbar interbody fusion[J]. Spine(phila Pa 1976),1995,20(3):356-361.
[12]
Chhabria M,Jani M,Patel S.New frontiers in the therapy of tuberculosis:fighting with the global menace[J].Mini Rev Med Chem,2009,9(4):401-430.
[13]
Rajasekaran S.The natural history of post-tubercular kyp hosisin children:radiological signs which predict late increase in deformity[J].J Bone Joint Surg Br,2010,83(7):954-962.
Lee SH,Sung JK,Park YM.Single-stage transpedicular decompression and posterior instrumentation in treatment ofthoracicandthoracolumbarspinaltuberculosis:a retrospective case seties[J].J Spinal Disord Tech,2012,19(8):595-602.
[21]
Machino M,Yukawa Y,Keigo I,et al.A new thoracic reconstruction technique"transforaminal thoracic interbody fusion":a preliminary report of clinical outcomes[J].Spine,2010,35(19):E1000-E1005.