Abstract：Objective To investigate the current conditions of the use of parenteral nutrition（PN）in Qilu Hospital of Shandong University,and analyze the factors that cause irrational prescriptions to provide references for the rational use of PN.Methods A statistical analysis was performed on a total of 18,806 PN prescriptions reviewed by pharmaceutical intravenous admixture services(PIVAS）from October to December 2019 in a hospital.The main,secondary,and general factors that caused the irrational use of PN were analyzed using the Pareto chart.Results The use of parenteral nutrition solution is basically consistent with the diagnosis and treatment needs of clinical departments,and the prescription design is basically reasonable.The proportion of irrational prescriptions was 1.14%.The irrational composition and ratio of the three basic nutrients of glucose,amino acids,and fat emulsion were the main factor bringing about the irrational PN prescriptions（with the cumulative composition ratio of 0%-80%）.While secondary factor was the unreasonable addition of other nutrients in PN prescriptions（with the cumulative composition ratio of 80%-90%）.The general factor were improper input operation of doctors and improper infusion methods（with the cumulative composition ratio of 90%-100%）.The ratio of unreasonable prescriptions of the two-in-one or all-in-one PN(1.26%)was significantly larger than that of the industrially produced three-cavity PN(0.41%),the difference was statistically significant(P<0.05).Conclusion Irrational clinical applications of PN were still partially existed.Both the nutrient composition and ratio of the PN prescriptions and the input operation of the doctors should be deeply.It should be deeply intervened,improved and standardized.Besides,the use of industrialized three-cavity bags to replace two-in-one or all-in-one nutritional solutions maybe expected to improved the rational use of PN.
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LIU Yun-ting. Analysis of application status of parenteral nutrition solution in a hospital. 中国当代医药, 2021, 28(18): 158-162.
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