Analysis on compliance of the proton-pump inhibitors for injection in clinical application
CHEN Mi-lin1 YANG Jing-ran2 ZHANG Hui-feng1 LIU Yu1▲ WANG Jia-zuo1 WANG Ming-xing1 DOU Ti-e1 GUO Wei-yi3
1.Department of Pharmacy,the First People′s Hospital of Yunnan Province,Kunming 650032,China;
2.College of Science,Ningbo University of Technology,Zhejiang Province,Ningbo 315211,China;
3.Kunming Food and Drug Test Institute,Yunnan Province,Kunming 650034,China
Abstract：Objective To investigate the compliance and rationality of clinical infusion of proton-pump inhibitors in a top three hospital in Yunnan Province.Methods Field research and investigation were used to analyze the irregularities in clinical infusion of proton-pump inhibitors in a top three hospital in Yunnan Province from October 21 to November 20,2019,including infusion flushing tube,infusion time,placement time,etc.Results There were some irregularities in clinical infusion,mainly focusing on drugs with special requirements such as infusion flushing tube,protecting from light and immediate use,which occupied 39.84%.Among them,559 cases(26.17%)failed to meet the requirements under flushing tube requirements,and the PPIs accounted for 70.43%.Among the infusion products,which were placed for a long time,parenteral nutrient solution and reduced glutathione accounted for 17.69% over 3 hours,and PPIs accounted for 35.54% placed for 1 hour.Conclusion According to the characteristics of PPIs,for drugs with infusion flushing tube,infusion time limit and compatibility requirements,the order of use should be adjusted to reduce the waiting time for clinical infusion,so as to avoid potential risks of clinical infusion in detail.
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