Clinical effect of Catalysis Decoction combined with Oxytocin in preventing postpartum hemorrhage
WU Qian1 XU Jie2▲ HAN Yue1
1.Graduate school,Hu′nan University of Traditional Chinese Medicine,Hu′nan Province,Changsha 410208,China;
2.Department of Gynaecoiogy,Changde Hospital Affiliated to Hu′nan University of Traditional Chinese Medicine,Hu′nan Province,Changde 415000,China
摘要目的 观察产妇在产程中及产后服用催生汤配合缩宫素预防产后出血的效果。方法 选取2019年3月~2020年5月于湖南中医药大学附属常德医院产科住院部自然分娩无妊娠期及分娩期并发症的60 例产妇作为研究对象,采用随机数字表法将其分为观察组与对照组,每组各30 例。观察组产妇在西医治疗的基础上,分别在宫口开3 cm、宫口开全及产后2 h 口服自拟催生汤1 剂;对照组产妇仅常规使用缩宫素治疗。观察两组产妇的预防产后出血效果及产后出血量。结果 观察组产妇的产后2、24 h 出血量少于对照组,差异有统计学意义(P<0.05)。观察组产妇治疗后24 h 的中医症状积分低于对照组,差异有统计学意义(P<0.05)。观察组产妇的产后出血发生率低于对照组,差异有统计学意义(P<0.05)。两组产妇的用药恶心呕吐发生率比较,差异无统计学意义(P>0.05)。结论 催生汤联合缩宫素能有效预防产后出血,用药不良反应较少。
Abstract:Objective To observe the effect of Catalysis Decoction combined with Oxytocin in preventing postpartum hemorrhage.Methods A total of 60 cases who delivered naturally without pregnancy and childbirth complications in the Department of Obstetrics,Changde Hospital Affiliated to Hu′nan University of Chinese Medicine from March 2019 to May 2020 were selected as the research objects.The patients were divided into observation group and control group by random number table method,with 30 cases in each group.In the observation group,on the basis of western medicine treatment,the puerpera in the uterine mouth opened for 3 cm,the uterine mouth opened for 2 h and the postpartum orally prepared 1 dose of Catalysis Decoction.The control group was treated with Oxytocin only.The preventive effect of postpartum hemorrhage and the amount of postpartum hemorrhage were compared between the two groups.Results The amount of postpartum bleeding at 2 and 24 h in the observation group were less than those in the control group,and the differences were statistically significant(P<0.05).The TCM symptom score 24 h after treatment in the observation group was lower than that in the control group,and the difference was statistically significant(P<0.05).The incidence of postpartum hemorrhage in the observation group was lower than that in the control group,and the difference was statistically significant(P<0.05).There was no significant difference in the incidence of nausea and vomiting between the two groups(P>0.05).Conclusion Catalysis Decoction combined with Oxytocin can effectively prevent postpartum hemorrhage,and has less adverse drug reactions.