Abstract：Objective To investigate the effect of high frequency repetitive transcranial magnetic stimulation(rTMS)on cognitive function of alcohol dependent patients.Methods Forty-four male patients with alcohol dependence who were hospitalized in Shenyang Mental Health Center from January 2019 to June 2019 were selected as the research subjects,and randomly divided into study group(22 cases)and control group(22 cases)according to the hospitalization number,odd-even number.The study group received rTMS treatment and the control group received pseudo stimulation.Both groups were treated for 8 weeks.The mini-mental assessment scale(MMSE)and the Montreal cognitive assessment scale(MoCA)were used to assess patients′ cognitive status at baseline,4 and 8 weeks of treatment.Results Before treatment,there was no significant difference in MMSE and MoCA scores between the two groups(P>0.05).After 4 and 8 weeks of treatment,the MMSE and MoCA scores of the study group were higher than those of the control group,the differences were statistically significant(P<0.05).The MMSE and MoCA scores of the study group after 4 and 8 weeks of treatment were higher than those before treatment,while those of the control group after 8 weeks of treatment were higher than those before treatment,the differences were statistically significant(P<0.05).There were no obvious adverse reactions in the two groups.Conclusion rTMS can promote the cognitive function recovery of alcohol-dependent patients with high safety,which is worthy of clinical promotion and application.
张云. 高频重复经颅磁刺激对酒精依赖患者认知功能的影响[J]. 中国当代医药, 2021, 28(22): 120-123.
ZHANG Yun. Effect of high frequency repetitive transcranial magnetic stimulation on cognitive function in alcohol-dependent patients. 中国当代医药, 2021, 28(22): 120-123.
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