Clinical effect of DCCIK immunotherapy combined with chemotherapy in the treatment of lung cancer
WANG Ling1 QIU Zhi-min2 DAI Yue1▲
1.Department of Nursing, Jiangxi Health Vocational College, Jiangxi Province, Nanchang 330052, China ;
2.Department of Comprehensive Oncology, Jiangxi Cancer Hospital, Jiangxi Province, Nanchang 330029, China
Abstract:Objective To investigate the long-term and short-term clinical effects of DCCIK immunotherapy combined with chemotherapy on patients with lung cancer.Methods The clinical data of 60 patients with lung cancer admitted to Jiangxi Cancer Hospital from January 2016 to June 2016 were retrospectively analyzed.According to different treatment methods, they were divided into group A and group B, with 30 patients in each group.Group A was treated with DCCIK combined with chemotherapy treatment methods, group B was treated with chemotherapy alone.The disease control rate, karnofsky (KPS) score, and long-term efficacy were compared between the two groups.Results After treatment,the total improvement rate of KPS in group A was higher than that in group B, and the difference was statistically significant (P<0.05).The 1-year survival rate of group A was higher than that of group B, the 2-year survival rate of group A was higher than that of group B, the median survival time of group A was higher than that of group B, and the differences were statistically significant (P<0.05).Conclusion DCCIK immunotherapy combined with chemotherapy is effective in the treatment of patients with lung cancer, which can significantly improve the quality of life of patients and increase the survival time of the disease.
王玲;邱志敏;戴月. DCCIK免疫治疗联合化疗治疗肺癌的临床效果[J]. 中国当代医药, 2021, 28(20): 106-108.
WANG Ling1 QIU Zhi-min2 DAI Yue1▲. Clinical effect of DCCIK immunotherapy combined with chemotherapy in the treatment of lung cancer. 中国当代医药, 2021, 28(20): 106-108.
Bray F,Ferlay J,Soerjomataram I,et al.Global cancer statistics 2018:GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries[J].CA Cancer Clin,2018,68(6):394-424.
Genestreti G,Grossi F,Genova C,et al.Third-and furtherline therapy in advanced non-small-cell lung cancer patients:an overview[J].Future Oncol,2014,10(13):2081-2096.
[5]
Song S,Bi M.Research progress of HGF/MET signaling pathway in EGFR-TKI resistance in non-small cell lung cancer[J].Zhongguo Fei Ai Za Zhi,2014,17(10):755-759.