Objective To evaluate the diagnostic value of point-of-care testing (POCT) in the risk assessment of patients with emergency chest pain.Methods From October 2016 to October 2018, 180 patients with emergency chest pain treated in emergency department of Beijing Nuclear Industry Hospital were selected as the research objects.They were divided into observation group (n=100) and control group (n=80) according to its detection method.The observation group used POCT technology to detect the relevant indicators, and the control group used the conventional laboratory method to detect.The emergency detention time, specimen detection time and clinical treatment time of detection reports were compared between the two groups.The emergency retention time, specimen detection time, detection report clinical disposal time of the two groups were compared, and the accuracy of POCT detection, the success rate of rescue,the incidence of cardiovascular events, and the accuracy of reexamination were compared between two groups.Results The emergency retention time, specimen detection time, clinical treatment time and hospitalization time of the observation group were all shorter than those of the control group, the differences were statistically significant (P<0.05).The sensitivity, specificity and accuracy of the two methods were not statistically significant, the differences were not statistically significant (P>0.05).The success rate of rescue and the accuracy of reexamination in the observation group were higher than those in the control group, while the incidence of cardiovascular events was lower than that in the control group, and the differences were statistically significant (P<0.05).Conclusion The application of POCT in patients with emergency chest pain is fast and reliable.It can accurately assess the dangerous level, improve the success rate of rescue and the accuracy of retest, reduce cardiovascular events.