Abstract：Objective To investigate the relationship between prothrombin fragment 1+2,D-dimer,Gensini score and prognosis of coronary heart disease(CHD).Methods A total of 114 patients with CHD admitted to our hospital from January 2017 to February 2018 were enrolled.According to the different prognosis of CHD,they were divided into the major adverse cardiovascular events (MACE) group (n=34) and the non-MACE group (n=80).The influencing factors of prognosis of CHD were analyzed.The risk factors of MACE were analyzed using COX model.Results The D-dimer and prothrombin fragment 1+2 in the non-MACE group were lower than those in the MACE group,the Gensini score in the non-MACE group was higher than that in the MACE group,with statistical significance (P＜0.05).There was no significant difference in male ratio,hypertension ratio,or left ventricular ejection fraction between the two groups (P＞0.05).A COX regression model was established.The occurrence of MACE was set as a dependent variable.The corrected multivariate COX regression analysis indicated D-dimer,prothrombin fragment 1+2,and Gensini score were independent predictors of MACE events,with statistical significance (P＜0.05).Conclusion Prothrombin fragment 1+2,D-dimer and Gensini score are independent predictors of CHD.Strengthening monitoring can provide a reliable theoretical basis in the guidance of clinical treatment.
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