Abstract:Objective To investigate the clinical effect of Ephedrine Nasal Drops with different postures in the prevention of barotrauma of the middle ear caused by hyperbaric oxygenation.Methods A total of 60 patients who underwent the hyperbaric oxygen therapy for the first time in our hospital from January 2014 to November 2017 were selected as objects.They were randomly divided into observation group (n=30)and control group (n=30).The two groups of patients were treated in the same capsule,and the Ephedrine Nasal Drops were used before entering the capsule on the 1st,2nd and 3rddays.Patients in the control group received Ephedrine on the supine position,while head-side in 45°on the horizontal position was adopted in the observation group.The occurrence of barotrauma of the middle ear,the extent of tympanic membrane damage,and hyperbaric oxygen therapy tolerance were compared in order to analyze and evaluate the effect of different positions of Ephedrine Nasal Drops on the prevention of barotrauma of the middle ear caused by hyperbaric oxygen therapy and the influence on patient′s tolerance.Results The incidence of the middle ear barotrauma in the observation group was 6.66%,which was significantly lower than that in the control group accounting for 26.66%,and the difference was statistically significant(P<0.05).The degree of tympanic membrane damage was significantly lighter than that in the control group,and the difference was statistically significant(P<0.05).The tolerance of hyperbaric oxygen treatment in the observation group was 93.33%,which was significantly higher than that in the control group accounting for 73.33%,and the difference was statistically significant(P<0.05).Conclusion Ephedrine Nasal Drops in patients with head-side in 45°on the horizontal position is helpful to reduce the incidence of barotrauma of the middle ear,alleviate the degree of tympanic membrane damage,and increase the patients′tolerance to hyperbaric oxygen therapy,which obtains a remarkable effect and is worthy of clinical reference and promotion.
彭龙娇;冯美莲;贺三娇;罗晓骁. 不同体位麻黄碱滴鼻预防高压氧所致中耳气压伤的临床研究[J]. 中国当代医药, 2018, 25(26): 100-102.
PENG Long-jiao;FENG Mei-lian;HE San-jiao;LUO Xiao-xiao. Clinical study of Ephedrine Nasal Drops with different postures in the prevention of barotrauma of the middle ear caused by hyperbaric oxygenation. 中国当代医药, 2018, 25(26): 100-102.