Abstract：Objective To observe the effect of ultra-early hyperbaric oxygen treatment on elderly patients of acute carbon monoxide poisoning.Methods 60 cases of elderly patients with severe carbon monoxide poisoning diagnosis criteria from January 2014 to December 2015 were randomly divided into the control group and the observation group，30 cases in each group.After admission，the patients in the two groups were given oxygen，dehydration reducing intracranial pressure，brain nutrition，improving cerebral blood circulation drugs and symptomatic treatment，the observation group were given above treatment to solicit the consent of patients and their families immediately after ultra early hyperbaric oxygen treatment.After treatment the clinical symptoms and signs，clinical neural function defect score（NDS）between the two groups before and after treatment were observed and compared.Results Before treatment，the NDS of the control group and the observation group respectively were （35.26±1.34），（34.46±2.23）scores，after treatment，the NDS of the control group and the observation group were respectively （28.37±2.45），（11.25±1.12）scores，there was no significant difference between the two groups before treatment，the scores of neurological deficits after treatment in the two groups was significantly lower than that before treatment respectively，the difference was statistically significant（P＜0.01）.After treatment，the total effective rate of the observation group was higher than that of the control group，the average hospitalization time was shorter than the control group，the incidence of delayed encephalopathy was lower than that of the control group，the difference was statistically significant （P＜0.05）.Conclusion Using ultra-early hyperbaric oxygen treatment can improve the hypoxia and ischemia state，effectively protect the brain tissue，reduce the incidence of delayed encephalopathy，worthy of clinical promotion.
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