Abstract：ObjectiveTo investigate the clinical significance of fractional exhaled Nitric Oxide(FeNO)test in asthmatic patients at different stages.Methods30 patients with asthma treated in our hospital from June to December 2016 were selected as asthma group of this study,and 30 non smokers in our hospital during the same period were selected as the control group.The FeNO values were compared between the two groups before treatment(T1),at 4 weeks(T2)and 12 weeks(T3)of treatment.ResultsAt T1,T2and T3,the FeNO values of patients in the asthma group were significantly higher than those in the control group,and the differences were statistically significant(P＜0.05).At T2,the FeNO value of patients in the asthma group was lower than T1,and the difference was statistically significant(P＜0.05).At T3,the FeNO value of patients in the asthma group was significantly lower than that of T1and T2,and the differences were statistically significant(P＜0.05).ConclusionThe FeNO value of patients in the asthma group at different stages are higher than those of healthy people,and with the increase of treatment time,the detection value of FeNO gradually decreased,and the FeNO test has a good guiding role in the treatment of asthma.
Ricciardolo FL，Sorbello V，Ciprandi G.A pathophysiological approach for FeNO：A biomarker for asthma[J].Allergologia Et Immunopathologia，2015，43（6）：609-616.
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