Abstract:Objective To investigate the clinical effect of biofeedback and oral administration of Desmopressin Acetate in the treatment of primary enuresis in children.Methods The clinical data of 60 children with primary enuresis admitted from March 2015 to March 2017 in our hospital were analyzed.According to the different treatment measures,they were evenly divided into control group(behavioral therapy)and observation group(biofeedback+oral administration of Desmopressin Acetate),30 cases in each groups.Before and after treatment,the urine osmotic pressure,antidiuretic hormone(ADH)and the total effectiveness rate in the two groups were observed.Results Before treatment,urinary osmotic pressure and ADH in children with primary enuresis were not significantly different(P>0.05).The urinary osmotic pressure and ADH in children both in the control group and observation group after treatment were higher than those before.After therapy,the two indexes in the observation group were superior to those in the control group(P<0.05).The total clinical effectiveness rate in the observation group was higher than that in the control group,the differences were statistically significant(P<0.05).Conclusion The biofeedback and oral administration of Desmopressin Acetate can significantly improve primary enuresis in children in a favorable effect,which is worthy of clinical promotion and application.
满杏禹;邹贤. 生物反馈、口服醋酸去氨加压素治疗儿童原发性遗尿症临床研究[J]. 中国当代医药, 2018, 25(11): 93-95.
MAN Xing-yu;ZOU Xian. Clinical study of biofeedback and oral administration of Desmopressin Acetate in the treatment of primary enuresis in children. 中国当代医药, 2018, 25(11): 93-95.
Delgado Nunes V,O'Flynn N,Evans J,et al.Management of enuresis in children and adolescents:summary of the NICE guideline[J].Praxis,2011,100(11):649-652
Stanton R,Ada L,Dean CM,et al.Biofeedback im proves activities of the lower limb after stroke:a system atic review[J].J Physiother,2011,57(3):145-155.
[7]
Austin PF,Ferguson G,Yan Y,et al.Combination therapy with desmopressin and an anticholinergic medication for nonresponders to desmopressin for monosymptomatic nocturnal enuresis:a randomized,double-blind,placebo-controlled trial[J].Pediatrics,2008,122(5):1027-1032.
ullally WJ,Hall K,Goldstein R.Efficacy of biofeedback in the treatm ent of migraine and tension type headaches[J].Pain Physician,2009,12(6):l005-1011.
[10]
Kim KH,Yu CS,Yoon YS,et al.Effectiveness of biofeedback therapy in the treatment of anterior resection syndrome after rectal cancer surgery[J].Dis Colon Rectum,2011,54(9):1107-1113.
Juul KV,Van Herzeele C,De Bruyne P,et al.Desmopressin melt improves response and compliance compared with tablet in treatment of primary monosymptomatic nocturnal enuresis[J].Eur J Pediatr,2013,172(9):1235-1242.
[17]
Kwak KW,Lee YS,Park KH,et al.Efficacy of desmopressin and enuresis alarm as first and second line treatment for primary monosymptomatic nocturnal enuresis:prospective randomized crossover study[J].J Urol,2010,184(6):2521-2526.
[18]
Ahmed AF,Amin MM,Ali MM,et al.Efficacy of an enuresis alarm,desmopressin,and combination therapy in the treatment of saudi children with primary monosymptomatic nocturnal enuresis[J].Korean J Urol,2013,54(11):783-790.